ArticleFrontiers in nutrition2025
Nutritional and inflammatory biomarkers in predicting spontaneous anastomotic leakage closure following enterocutaneous fistula resection: the role of postoperative CRP-lymphocyte ratio.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Prolonged bowel disuse under parenteral nutrition elevates risk of acalculous cholecystitis in patients with low-output enterocutaneous fistulas.Frontiers in nutrition · 2026Article
- Malnutrition as an independent risk factor for fluoropyrimidine- and oxaliplatin-based chemotherapy-induced cardiovascular toxicity in colorectal cancer: a single-center retrospective cohort study.Frontiers in cardiovascular medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: To determine the correlation between the C-reactive protein-lymphocyte ratio (CLR) and the spontaneous resolution of anastomotic leakage (AL) subsequent to the resection of enterocutaneous fistulas (ECF). Methods: In this retrospective cohort analysis, we examined adult patients who experienced AL following ECF resection from January 2019 to January 2024. Observations continued for 90 days post-surgery, during which CLR values were recorded at designated intervals. The relationship between CLR and the spontaneous resolution of leakage by 30 and 90 days was evaluated using logistic regression and restricted cubic splines. Results: Out of 107 participants, 35 (32.7%) exhibited spontaneous resolution of leakage within 30 days, while 90 (84.1%) did so by the 90-day mark. A significant association was noted between CLR on day 7 post-leakage and 30-day resolution (OR = 0.97, 95%CI: 0.94-0.99, Conclusion: Decreasing CLR subsequent to leakage may be one of supportive predictor for spontaneous closure of AL following ECF resection.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.