Evidence map›Paper›PMID 41458990›Full record

ReviewFrontiers in cardiovascular medicine2025

Current perspectives on risk prediction and genetic basis of Brugada syndrome.

Priya Bhardwaj, Dorte Stavnem, Stine Bøttcher Jacobsen, Bo Gregers Winkel, Jacob Tfelt-Hansen

Abstract readReview
In one paragraph

Review in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Priya BhardwajDepartment of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Dorte StavnemDepartment of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Stine Bøttcher JacobsenDepartment of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Bo Gregers WinkelDepartment of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Jacob Tfelt-HansenDepartment of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brugada syndrome (BrS) is an inherited arrhythmia disorder and a major cause of sudden cardiac death below 50 years. Despite more than three decades of research, diagnosis and risk prediction remain challenging due to variable presentation and incomplete understanding of its genetic basis. The Brugada electrocardiographic pattern is central to diagnosis but lacks specificity, while different scoring systems offer structured assessment yet perform inconsistently in asymptomatic or intermediate-risk patients.

Indexed as

arrhythmiaarrhythmic syncopeatrial fibrillationBRUGADA-RISK modelBrugada syndromeelectrocardiographic patternSCN5AShanghai score

Identifiers

PMID41458990
PMCPMC12740877

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.