ArticleFrontiers in cardiovascular medicine2025
Temporal trends in mortality involving atrial fibrillation and rheumatic heart disease: a 25-year nationwide analysis.
Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Patterns and trends of mortality in patients with arrhythmia and cerebrovascular disease in the United States: a nationwide analysis of older adults.Scientific reports · 2026Article
- Trends and disparities in deaths involving atherosclerotic cardiovascular disease and stroke-related conditions among U.S. adults, 1999-2025.Frontiers in cardiovascular medicine · 2026Article
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14 authors.
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Abstract
Background: Atrial fibrillation (AF) and rheumatic heart disease (RHD) can coexist with potential for serious complications. Trends involving both conditions remain unexplored and this study aims to explore them. Methods: Nationwide mortality records were obtained from the Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research (CDC-WONDER) database from 1999 to 2023 among U.S. adults >45 years with AF (ICD-10 code: I48) and RHD (I05-I09). Age-adjusted mortality rates (AAMRs) were calculated per 100,000 population and stratified by demographic variables. Joinpoint regression analysis was used to determine the average and annual percent change (AAPC and APC). Results: From 1999 to 2023, a total of 36,701 deaths were reported among individuals aged >45 years with AF and RHD in the U.S. The AAMR increased from 1.04 in 1999 to 2.00 in 2023 (AAPC: 2.78; Conclusion: Trends in AF and RHD mortality increased lately. Higher trends observed in women, rural areas, the West region, NH white population and inpatient medical facilities.
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