Evidence map›Paper›PMID 41458969›Full record

ReviewFrontiers in pharmacology2025

Preparation and biomedical application of light-responsive hydrogels based on natural products.

Xinyi Fan, Haihua Shang, Leyuan Ji, Shitang Ma, Maoliang Liao

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xinyi FanCollege of biological and pharmaceutical engineering, West Anhui University, Lu'an, China.
Haihua ShangTianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College and Chinese Academy of Medical Sciences, Tianjin, China.
Leyuan JiCollege of Traditional Chinese Medicine, Anhui University of Chinese Medicine, Hefei, China.
Shitang MaCollege of biological and pharmaceutical engineering, West Anhui University, Lu'an, China.
Maoliang LiaoCollege of biological and pharmaceutical engineering, West Anhui University, Lu'an, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This article systematically reviews the light-responsive hydrogels based on natural products, with a focus on their extensive applications in the field of biomedicine. Regarding the preparation methods, the article elaborates on the physical self-assembly, chemical crosslinking agent method, photocrosslinking method, and free radical polymerization method. The biomedical application section introduces their applications in drug release and wound healing based on the mechanisms of photochemical reactions, photoisomerization reactions, and photothermal reactions. In terms of quality evaluation frameworks, the natural light-responsive hydrogels evaluation frameworks is summarized, and the shortcomings of the existing evaluation frameworks are analyzed. Finally, the article summarizes its application potential and development bottlenecks, looks forward to future research directions, and proposes targeted development suggestions, thereby promoting its wider applications in deep disease treatment and personalized medicine.

Indexed as

biomedical applicationsFundamental characteristicslight-responsive hydrogelsnatural productsphysical and chemical crosslinkingquality evaluation frameworks

Identifiers

PMID41458969
PMCPMC12739651

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.