Evidence map›Paper›PMID 41458860›Full record

ArticleCureus2025

When Fitness Turns Fatal: A Case of Severe Rhabdomyolysis in a 20-Year-Old Male.

Wardah Tariq, Habeeb Kamal, Aung M Naing, Farah Shahid, Suhail Ahmed

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wardah TariqGeneral Medicine, University Hospitals of Leicester NHS Trust, Leicester, GBR.
Habeeb KamalGeneral Medicine, University Hospitals of Leicester NHS Trust, Leicester, GBR.
Aung M NaingGeneral Medicine, University Hospitals of Leicester NHS Trust, Leicester, GBR.
Farah ShahidGeneral Medicine, University Hospitals of Leicester NHS Trust, Leicester, GBR.
Suhail AhmedGeneral Medicine, University Hospitals of Leicester NHS Trust, Leicester, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exertional rhabdomyolysis (ER) is a potentially life-threatening condition caused by intense or prolonged physical activity, leading to skeletal muscle injury and leakage of intracellular components into the circulation. Although commonly recognized in athletes and military recruits, it may also occur in previously healthy individuals undertaking unaccustomed high-intensity exercise. We report a 20-year-old male with no significant medical history who presented with muscle soreness, dysuria, and dark urine following increased gym activity. Laboratory studies demonstrated extremely elevated creatine kinase (CK) levels consistent with severe ER; however, kidney function remained entirely normal despite the markedly elevated CK, a feature that makes this case clinically distinctive. Prompt recognition and aggressive intravenous fluid resuscitation resulted in full recovery. This case provides educational value by emphasizing that even "sky-high" CK levels do not invariably lead to renal impairment when ER is rapidly identified and managed, underscoring the importance of early intervention and careful monitoring in individuals engaging in unsupervised intense exercise.

Indexed as

acute kidney injurycase reportcreatine kinaseexercise-induced muscle injuryexertional rhabdomyolysis

Identifiers

PMID41458860
PMCPMC12741298

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.