ArticleCureus2025
An Older Woman With Postoperative Breast Metastasis From Ascending Colon Cancer Successfully Treated With Pembrolizumab.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
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Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metastatic breast cancer is sporadic, and colorectal cancer as its primary site is even more uncommon. Here, we report a case of metastatic breast cancer in a patient who had undergone surgery for ascending colon cancer. An 82-year-old woman was diagnosed with a breast tumor that was identified as metastatic by immunohistochemical staining, mainly cytokeratin 20 and cytokeratin 7. Additionally, the patient had developed lymphadenopathy in the abdominal aortic region. Because of microsatellite instability-high (MSI-H) status, pembrolizumab was chosen for treatment, and after 23 cycles, all metastatic lesions were no longer detectable. The diagnosis of metastatic breast cancer is challenging, but immunohistochemical staining facilitated an accurate diagnosis in this case. We also noted that the histological type of this case was medullary carcinoma. Furthermore, as far as we could find out, this is the first reported case of colon cancer metastasis to the breast successfully treated with immune checkpoint inhibitors.
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