ArticleCureus2025
Hyperammonemic Encephalopathy Caused by Obstructive Urinary Tract Infection Due to Urease-Positive Corynebacterium riegelii in an Elderly Woman: A Case Report.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Hyperammonemia typically results from hepatic dysfunction, but obstructive urinary tract infection (UTI) caused by urease-producing bacteria can rarely induce severe hyperammonemia and encephalopathy. We describe a 76-year-old woman with chronic voiding dysfunction who presented with fever and coma, with a markedly elevated serum ammonia level of 380 μg/dL despite normal liver function. Urinalysis revealed markedly alkaline urine and pyuria. Head computed tomography (CT) and magnetic resonance imaging showed no acute abnormalities. Abdominal CT demonstrated marked bladder distention and no findings suggestive of chronic liver disease. Bladder decompression and piperacillin/tazobactam therapy led to rapid improvement, with ammonia falling to 70 μg/dL and full recovery of consciousness within 48 hours. Urine culture later yielded
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