ArticleCureus2025
Delayed Gastric Emptying After Classical Pancreaticoduodenectomy Versus Pylorus-Preserving Pancreaticoduodenectomy With Billroth II Retrocolic Reconstruction in Patients With Cancer.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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Authors and funding
3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Introduction Delayed gastric emptying (DGE) is a common complication after pancreaticoduodenectomy (PD), associated with prolonged hospitalization and delayed initiation of adjuvant therapy. Surgical reconstruction technique may influence postoperative gastric motility. This single-center study evaluated the association between the type of PD (classical vs. pylorus-preserving PD (PPPD)) and the incidence of DGE in patients undergoing standardized retrocolic Billroth II reconstruction for malignant disease. Materials and methods We conducted a retrospective observational study of 15 patients who underwent PD for malignant disease between June 2021 and June 2022 at a tertiary oncology center. All patients underwent retrocolic Billroth II reconstruction. Clinically relevant DGE (grades B and C) was defined according to the International Study Group of Pancreatic Surgery criteria. Results DGE occurred in 46% (7/15) of patients overall. The incidence was significantly higher after classical PD (77.8%, 7/9) compared with no cases in the PPPD group (0/6; p = 0.007). Among patients with DGE, 28.6% (2/7) tolerated solid intake before postoperative week three, while 71.4% (5/7) did so after week three. Ninety-day mortality was 0% in both groups. At study closure, overall survival was 77.8% in the classical PD group and 100% in the PPPD group (p = 0.642), reported descriptively due to the limited sample size. Conclusion PPPD appeared to be associated with a lower frequency of clinically relevant DGE after standardized retrocolic Billroth II reconstruction. These preliminary findings suggest that meticulous, tension-free reconstruction may help optimize postoperative gastric motility. Larger studies are needed to validate these exploratory observations.
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