ArticleCureus2025
Transient Psychiatric Disturbances Following Bifrontal Craniotomy for Suprasellar Tumors.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionBifrontal craniotomy for suprasellar tumors may lead to the development of transient psychiatric disorders associated with frontal lobe involvement; however, published data on this issue remain limited.
methodsA retrospective analysis was performed on 70 patients who underwent surgery via the bifrontal approach between 2018 and 2023. Psychiatric evaluation was conducted before and after surgery using the Hospital Anxiety and Depression Scale (HADS).
resultsTemporary psychiatric disturbances were observed in 39 of 70 patients (56%): apathy (n=9), depression (n=4), and disinhibition (n=1). Symptom onset occurred on postoperative days 3-7, with a duration of 2-8 weeks. Risk factors included tumor size >4 cm (p=0.03) and operative time >5 hours (p=0.04). Full recovery was noted in all patients within three months.
conclusionTransient psychiatric disorders after bifrontal craniotomy are common but self-limiting in nature. Early psychiatric consultation is recommended.
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