ArticleCureus2025
A Case of Anti-3-Hydroxy-Methylglutaryl-Coenzyme a Reductase (Anti-HMGCR) Immune-Mediated Necrotizing Myopathy.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
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Abstract
Anti-3-hydroxy-methylglutaryl-coenzyme A reductase (Anti-HMGCR) immune-mediated necrotizing myopathy (INMN) is a type of autoimmune myopathy that is commonly associated with a history of statin use. In this case report, we present a 47-year-old man with a history of statin use who was admitted to the hospital with elevated creatine kinase and progressive muscle weakness. Muscle biopsy and myositis panel confirmed the diagnosis of anti-HMGCR IMNM. Creatine kinase levels and symptoms improved with the initiation of glucocorticoids, mycophenolate mofetil, and rituximab. This case report expresses the need for continued research into the treatment guidelines as well as the long-term effects of anti-HMGCR IMNM.
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