Evidence map›Paper›PMID 41458712›Full record

ArticleCureus2025

Acute Symptomatic Hyponatremia With Reversible Diffuse Brain Edema on CT.

Yasutaka Yoshiike, So Sakamoto, Chikao Ito, Isao Takahashi

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yasutaka YoshiikeEmergency Medicine, Asahi General Hospital, Asahi, JPN.
So SakamotoEmergency Medicine, Asahi General Hospital, Asahi, JPN.
Chikao ItoEmergency Medicine, Asahi General Hospital, Asahi, JPN.
Isao TakahashiEmergency Medicine, Asahi General Hospital, Asahi, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyponatremia-induced altered consciousness is a common clinical presentation, and brain edema is a well-known complication. However, few reports describe detailed imaging findings or discuss the neurological prognosis in such cases. We report a case of acute symptomatic hyponatremia in which diffuse brain edema was evident on CT at admission. The imaging findings resolved with appropriate treatment during hospitalization, and the patient recovered with no neurological sequelae. This case demonstrates that brain edema caused by hyponatremia can be reversible and does not necessarily predict a poor neurological outcome. It also highlights the importance of considering water intoxication in patients presenting with hyponatremia and diffuse brain edema. Additionally, it suggests that CT findings may assist in guiding treatment strategies for severe hyponatremia.

Indexed as

acute hyponatremiabrain edemahypertonic salinewater intoxicationwater restriction

Identifiers

PMID41458712
PMCPMC12743601

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.