ArticleCureus2025
Refractory Penile Condyloma Acuminatum in an Elderly Man Receiving Vedolizumab and Azathioprine.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We report a case of an 83-year-old man who developed treatment-resistant penile condyloma acuminatum while receiving vedolizumab and azathioprine for ulcerative colitis. The patient had not engaged in sexual intercourse for more than five years. Laboratory findings revealed mild immunosuppression with decreased B-cell lymphocytes and low immunoglobulin A levels. The combined use of vedolizumab and azathioprine may have impaired genital mucosal immunity, leading to reactivation of latent human papillomavirus (HPV) infection. To our knowledge, condyloma acuminatum developing during vedolizumab therapy has rarely been reported, and this case suggests a potential association between vedolizumab and HPV reactivation.
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Registered trials
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