Evidence map›Paper›PMID 41458651›Full record

ArticleCureus2025

Bifascicular Block Associated With Myocardial Infarction: A Marker of Proximal Left Anterior Descending Artery Occlusion Confirmed by the Artificial Intelligence-Based Smartphone App Queen of Hearts.

Lucio Giuseppe Granata, Francesco Russo, Simona Giubilato, Marilena Scarabelli, Francesco Amico

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lucio Giuseppe GranataDepartment of Clinical and Experimental Medicine, Cardiology Unit, University Hospital Polyclinic G. Martino, Messina, ITA.
Francesco RussoDepartment of Clinical and Experimental Medicine, Cardiology Unit, University Hospital Polyclinic G. Martino, Messina, ITA.
Simona GiubilatoCardiology Division, Cannizzaro Hospital, Catania, ITA.
Marilena ScarabelliCardiology Division, Cannizzaro Hospital, Catania, ITA.
Francesco AmicoCardiology Division, Cannizzaro Hospital, Catania, ITA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In a clinical context highly suggestive of acute coronary syndrome (ACS), the presence of a bifascicular block (BFB) should be considered a potential ST-elevation myocardial infarction (STEMI) equivalent. A right bundle branch block (RBBB) may obscure accurate assessment of the ST segment, potentially masking ischemic changes. Therefore, in patients with suspected ACS, BFB (RBBB and left anterior fascicular block), whether new or pre-existing, should be managed as a high-risk finding and treated according to STEMI protocols if clinical suspicion is strong. We report the case of a man in his 70s with multiple cardiovascular risk factors who was admitted for chest pain and hypotension. The ECG revealed a new (or presumably new) BFB, consisting of RBBB and left anterior fascicular block, associated with QRS-concordant anterior ST-segment elevation extending to lateral leads. Urgent coronary angiography demonstrated a proximal left anterior descending (LAD) artery subocclusion, which was successfully treated with primary percutaneous coronary intervention and drug-eluting stent implantation. The artificial intelligence (AI)-based smartphone application

Indexed as

artificial intelligencebifascicular blockheart failure with reduced ejection fraction (hfref)left anterior descending arteryleft anterior fascicular blockocclusive myocardial infarctionqueen of heartsright bundle branch blockst-elevation myocardial infarction (stemi)stemi equivalent

Identifiers

PMID41458651
PMCPMC12742895

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.