Evidence map›Paper›PMID 41458635›Full record

ArticleCureus2025

An Incidentally Detected Synthetic Fiber Embedded in the Corneal Stroma: A Report of a Rare Case.

Tatsuya Mimura, Yui Nishijima, Daisuke Hasegawa, Satoko Kujiraoka, Naoyuki Matsumoto

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tatsuya MimuraOphthalmology, Teikyo University School of Medicine, Tokyo, JPN.
Yui NishijimaDepartment of Ophthalmology, Tsurumi University School of Dental Medicine, Yokohama, JPN.
Daisuke HasegawaDepartment of Ophthalmology, Tsurumi University School of Dental Medicine, Yokohama, JPN.
Satoko KujiraokaDepartment of Diagnostic Pathology, Tsurumi University Dental Hospital, Yokohama, JPN.
Naoyuki MatsumotoDepartment of Pathology, Tsurumi University School of Dental Medicine, Yokohama, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Corneal foreign bodies (CFBs) are typically caused by the penetration of external materials such as metallic particles, concrete fragments, or plant matter into the corneal tissue and are usually accompanied by intense pain or a foreign-body sensation. We report an extremely rare case of an intrastromal CFB composed of synthetic fiber, which was discovered incidentally in an asymptomatic patient and confirmed histopathologically. A 54-year-old woman presented with bilateral visual impairment due to cataract. Slit-lamp examination revealed bilateral cataracts and a curved, white, linear foreign body approximately 1 mm in length embedded within the corneal stroma of the right eye. The patient had no history of ocular trauma or surgery. Review of anterior segment photographs taken five years earlier for dry eye evaluation demonstrated an identical finding in the same location, indicating that the lesion had been present for years without symptoms. The foreign body was removed under slit-lamp visualization using a 27-gauge needle and forceps. The extracted material was a slender filament lacking cellular components, consistent with a non-biological synthetic fiber. Following removal, the corneal opacity improved. A review of the literature identified reports of conjunctival granulomas or chronic inflammatory reactions caused by synthetic or cotton fibers, as well as intraocular penetration of fibers following ocular surgery or trauma; however, all previously reported cases were symptomatic. Synthetic fibers, commonly present in clothing and indoor environments, can adhere to the ocular surface and, in rare instances, penetrate into the corneal stroma even in the absence of trauma or symptoms. This case highlights a previously unrecognized route of fiber intrusion and suggests that synthetic fibers should be considered in the differential diagnosis of asymptomatic corneal opacities.

Indexed as

asymptomatic lesioncorneal foreign bodyhistopathologyintrastromal opacitynon-biological materialocular surfaceslit-lamp examinationsynthetic fiber

Identifiers

PMID41458635
PMCPMC12739890

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