Evidence map›Paper›PMID 41458586›Full record

ArticleFrontiers in oncology2025

Proton-boron capture interaction enhances killing of radiation resistant cancer cells.

Dalong Pang, Mira Jung, Alfredo Velena, William Parke, Anatoly Dritschilo

Abstract read
In one paragraph

Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dalong PangDepartment of Radiation Medicine, Georgetown University Medical Center, Washington, WA, United States.
Mira JungDepartment of Radiation Medicine, Georgetown University Medical Center, Washington, WA, United States.
Alfredo VelenaDepartment of Radiation Medicine, Georgetown University Medical Center, Washington, WA, United States.
William ParkeDepartment of Physics, George Washington University, Washington, WA, United States.
Anatoly DritschiloDepartment of Radiation Medicine, Georgetown University Medical Center, Washington, WA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/objectives: Studies involving the interaction of protons with boron ( Methods: Cell survival and DNA damage endpoints were analyzed in radiation resistant SQ-20B cells and in radiation sensitive MCF-7 cancer cells after exposure to Results: Exposure of cells to BSH Conclusions: Our data show a small enhancement of cell killing by proton radiation in the presence of BSH

Indexed as

boronBSHcell survivalirradiationMCF-7protonSQ-20BγH2AX

Identifiers

PMID41458586
PMCPMC12738170

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.