Evidence map›Paper›PMID 41458520›Full record

ArticleFrontiers in medicine2025

Association between CRP-TyG index and hepatic synthetic function in post-myocardial infarction ICU patients.

Jiao Bao, Jiejun Hu, Xiangyin Lv

Abstract read
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jiao BaoDepartment of Emergency, Affiliated Dongyang Hospital, Wenzhou Medical University, Dongyang, Zhejiang, China.
Jiejun HuDepartment of Emergency, Affiliated Dongyang Hospital, Wenzhou Medical University, Dongyang, Zhejiang, China.
Xiangyin LvDepartment of Gastroenterology, Affiliated Dongyang Hospital, Wenzhou Medical University, Dongyang, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To determine whether the CRP-TyG index (CTI)-a composite of systemic inflammation and insulin resistance-is independently associated with early hepatic synthetic function in post-myocardial infarction (MI) ICU patients within 24 h. Methods: Single-center, retrospective cross-sectional study of 286 consecutive post-MI ICU patients (standardized laboratory sampling within 24 h). CTI integrated C-reactive protein with the triglyceride-glucose index. Outcomes were serum albumin (ALB), prealbumin (PA), and the total bilirubin-to-albumin ratio (TBIL/ALB). Associations were estimated using ordinary least squares with prespecified covariate adjustment; nonlinearity was tested using restricted cubic splines. Incremental discrimination was assessed via AUC, net reclassification improvement (NRI), and integrated discrimination improvement (IDI). Prespecified subgroups (sex, age ≤/>70 years) and sensitivity analyses (excluding deaths, pressor users, CRRT) evaluated robustness. Results: Higher CTI was independently associated with lower ALB ( Conclusion: Within 24 h after myocardial infarction surgery, elevated CTI was associated with decreased albumin and prealbumin levels, but not TBIL/ALB ratio. The associations were the same across sex and age categories.

Indexed as

albumin (ALB)CRP-TyG indexhepatic synthetic functionintensive care unitmyocardial infarction

Identifiers

PMID41458520
PMCPMC12738846

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.