Evidence map›Paper›PMID 41458431›Full record

SynthesisFrontiers in public health2025

Optimal dose of aquatic exercise for improving muscle strength in older adults: a Bayesian model-based meta-analysis.

Yifei Wang, Jin Zhao, Mingchen Gao, Xiaobin Wu

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yifei WangSchool of Physical Education, Chengdu Sport University, Chengdu, Sichuan, China.
Jin ZhaoSports Teaching and Research Department, Lanzhou University, Lanzhou, Gansu, China.
Mingchen GaoSchool of Physical Education, Chengdu Sport University, Chengdu, Sichuan, China.
Xiaobin WuSchool of Physical Education, Chengdu Sport University, Chengdu, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Amid global population aging, the progressive loss of muscle strength is a critical challenge compromising the functional independence of older adults. This study aimed to systematically quantify the dose-response relationship between various doses of aquatic exercise (frequency, session duration, total weekly duration, period, and intensity) and muscle strength in healthy older adults through a Bayesian model-based meta-analysis, in order to identify the optimal exercise protocol and inform precision exercise prescription. Methods: PubMed, Embase, Cochrane Library, Web of Science, China National Knowledge Infrastructure (CNKI), and Wan Fang Data were systematically searched for RCTs on aquatic exercise and older adults' muscle strength up to March 2025. A conventional meta-analysis evaluated overall effects, followed by a Bayesian model-based dose-response meta-analysis using cubic restricted splines to quantify non-linear relationships. Standardized mean difference (SMD, with 95% CI/CrI) served as the effect measure. Results: A total of 13 RCTs ( Conclusion: Aquatic exercise is an effective strategy for improving muscle strength in healthy older adults, with its benefits demonstrating significant non-linear dose-response relationships. To maximize efficacy, the optimal recommended protocol consists of 2-3 sessions per week, each lasting approximately 40 min, at a moderate-to-high intensity (Borg RPE 10-12), and should be adopted as a long-term strategy. However, substantial heterogeneity and evidence of publication bias suggest cautious interpretation of pooled effects. Systematic review registration: Identifier: CRD420250654651.

Indexed as

ExerciseMuscle StrengthAgedBayes TheoremFemaleHumansMaleMiddle Agedaquatic exercisedose–response analysismeta-analysismuscle strengtholder adults

Identifiers

PMID41458431
PMCPMC12741266

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.