ArticleJournal of asthma and allergy2025
Inhalant-Specific IgE Profiles to Guide the Clinical Management and Prevention of Children with Respiratory Allergies in Fuzhou: A Cross-Sectional Cohort Study Based on ImmunoCAP.
Article in Journal of asthma and allergy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Pandemic-Associated Sensitization Patterns and Burden in Chinese Children with Allergic Rhinitis: A Retrospective Phase-Stratified Study.Journal of asthma and allergy · 2026Article
- Research on pollen allergy in Fuzhou, China: from the online public concern surveys to pollen monitoring.Frontiers in public health · 2026Article
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7 authors.
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Abstract
Rational: The incidence of pediatric respiratory allergic diseases is rising annually. However, no study has systematically investigated the spectrum of inhalant allergens in children from Fuzhou, China, using ImmunoCAP assay technology and cohort analysis. This study aimed to characterize the distribution of allergen-specific IgE (sIgE) in children aged 0-14 years with respiratory allergies in Fuzhou, providing theoretical support for etiological diagnosis, treatment, and prevention. Methods: A total of 196 children underwent allergen screening: 116 diagnosed with allergic rhinitis (AR) and 80 with asthma (AS). Serum sIgE antibodies against inhalant allergens were detected using the ImmunoCAP system. Results: In the AR group, Dermatophagoides pteronyssinus (d1) showed the highest sensitization rate (112/116), followed by Dermatophagoides farinae (d2) (110/116). In the AS group, d1 and d2 had equally high positivity rates (both 78/80), while Blattella germanica (i6) sensitization was significantly higher in AS than in AR. Sensitization to the animal epithelium panel (ex1) differed significantly between diseases in the 4-6-year age group. Correlation analysis revealed a strong positive correlation between tree pollen mix (tx5) and weed pollen mix (wx5) in both groups, and a significant correlation between d2 and d1. Conclusion: Dermatophagoides pteronyssinus (d1) and D. farinae (d2) are the predominant allergens in pediatric respiratory allergies in Fuzhou. This study offers valuable insights for preventing and treating these conditions.
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