ReviewClinical practice and epidemiology in mental health : CP & EMH2025
Emotional Disturbances and Crohn's Disease.
Review in Clinical practice and epidemiology in mental health : CP & EMH, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Attentional variability as a cognitive marker of clinical activity in Crohn's disease.Crohn's & colitis 360 · 2026Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: This review aims to explore the psychological, psychiatric, and neurocognitive dimensions of Crohn's disease. We examine the bidirectional interactions between the gut and brain, analyze the most widely used psychological assessment tools, and discuss current intervention models. Methods: A comprehensive narrative review was conducted, integrating the literature research findings of , psychosomatic medicine, neuropsychology, psychoneuroimmunology, and gut-brain axis. Attention was given to validated psychometric tools and emerging therapeutic approaches. Results: The evidence reveals a consistent link between CD and emotional disturbances, cognitive deficits, and altered gut-brain communication. Common neuropsychological impairments include deficits in attention, memory, and executive functioning. Anxiety, depression, and alexithymia are prevalent in CD patients and are associated with worse disease outcomes. Cognitive Behavioral Therapy (CBT), Acceptance and Commitment Therapy (ACT), and mindfulness-based interventions have demonstrated efficacy in enhancing both psychological well-being and disease management. Discussion: Findings confirm the link between Crohn's disease, emotional disturbances, and cognitive deficits, highlighting the need to distinguish between primary impairments of inflammatory/neurobiological origin and those secondary to psychological distress or low illness insight. Key gaps remain regarding how these mechanisms interact over time and the long-term effects of psychological interventions. Integrating psychological assessment and support into clinical care is crucial for enhancing adherence, resilience, and overall quality of life. Conclusion: Understanding CD through a biopsychosocial lens highlights the necessity of integrating psychological assessment and intervention into standard IBD care. Early identification and tailored treatment of emotional and cognitive disturbances can significantly improve patients' quality of life and overall clinical outcomes.
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Registered trials
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