Evidence map›Paper›PMID 41458288›Full record

ArticleCanadian respiratory journal2025

Upregulation of

Kang-Kang Hong, Guo-Sheng Li, Rong-Quan He, Zhi-Guang Huang, Yi-Zhi Feng, Jin-Liang Kong, Lao-Dong Li

Abstract read
In one paragraph

Article in Canadian respiratory journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Upregulation ofCanadian respiratory journal · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kang-Kang HongDepartment of Geriatric Medicine, The Fourth Affiliated Hospital of Guangxi Medical University, LiuZhou, Guangxi, China, gxmu.edu.cn.ORCID 0000-0003-0922-7909
Guo-Sheng LiDepartment of Cardiothoracic Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China, gxmu.edu.cn.
Rong-Quan HeDepartment of Medical Oncology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China, gxmu.edu.cn.
Zhi-Guang HuangDepartment of Pathology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China, gxmu.edu.cn.ORCID 0000-0003-4457-9491
Yi-Zhi FengWard of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China, gxmu.edu.cn.
Jin-Liang KongWard of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China, gxmu.edu.cn.ORCID 0000-0003-4065-7886
Lao-Dong LiWard of Pulmonary and Critical Care Medicine, The Fourth Affiliated Hospital of Guangxi Medical University, Liuzhou, Guangxi, China, gxmu.edu.cn.ORCID 0000-0002-6603-695X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Noncystic fibrosis (non-CF) bronchiectasis is a chronic respiratory disease characterized by irreversible bronchial dilation, with an increasing global prevalence and substantial clinical burden. Despite the advances in symptomatic management, the underlying molecular mechanisms remain poorly understood. Transcription factor DP-1 ( Methods: Gene expression data from the Gene Expression Omnibus dataset GSE97298 (27 patients with bronchiectasis vs. nine healthy controls) were analyzed to identify differentially expressed genes (DEGs) using edgeR (log Results: In total, 355 DEGs were identified (45 upregulated and 310 downregulated genes). Conclusion: This study demonstrated the synergistic upregulation of

Indexed as

BronchiectasisCell Cycle ProteinsAgedCase-Control StudiesFemaleHumansMaleMiddle AgedProtein Interaction MapsProtein Serine-Threonine KinasesUp-RegulationCDC7 protein, humanCell Cycle ProteinsProtein Serine-Threonine KinasesbiomarkerbronchiectasisCDC27cell cycleTFDP1

Identifiers

PMID41458288
PMCPMC12740773

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.