Evidence map›Paper›PMID 41458211›Full record

ArticleFrontiers in genetics2025

Automatic detection of n-degree family members.

Emil M Pedersen, Jette Steinbach, Carsten B Pedersen, Andrew J Schork, Morten D Krebs, Bjarni J Vilhjálmsson, Florian Privé

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Emil M PedersenNational Centre for Register-Based Research, Aarhus University, Aarhus, Denmark.
Jette SteinbachNational Centre for Register-Based Research, Aarhus University, Aarhus, Denmark.
Carsten B PedersenNational Centre for Register-Based Research, Aarhus University, Aarhus, Denmark.
Andrew J SchorkInstitute of Biological Psychiatry, Mental Health Center - Sct Hans, Copenhagen University Hospital, Copenhagen, Denmark.
Morten D KrebsInstitute of Biological Psychiatry, Mental Health Center - Sct Hans, Copenhagen University Hospital, Copenhagen, Denmark.
Bjarni J VilhjálmssonNational Centre for Register-Based Research, Aarhus University, Aarhus, Denmark.
Florian PrivéNational Centre for Register-Based Research, Aarhus University, Aarhus, Denmark.

Funding

Improving the interpretability of genetic studies of major depressive disorder to identify risk genesR01MH130581 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JONATHAN FLINT, KENNETH SEEDMAN KENDLER · 2022 to 2026
$2.8M
Risk Pathways to Major Depression: Integrating Genetic-Epidemiological, Developmental, and Molecular Genetic Strategies in Danish and Swedish National RegistersR01MH139865 · NIMH · VIRGINIA COMMONWEALTH UNIVERSITY · PI KENNETH SEEDMAN KENDLER, Andrew J Schork · 2025 to 2026
$1.1M
NIMH NIH HHS R01 MH130581NIMH NIH HHS R01 MH139865
6 · The paper itself

Abstract

Family-based genetic studies often require the identification of relatives up to a specified degree, but existing tools are either restricted to second-degree relatives, return entire connected pedigrees, or require multiple pre- or post-processing steps. We implemented five new functions, namely,

Indexed as

family-based studiesgenetic epidemiologygraph theorykinship matrixpedigree analysisR packagetrio data

Identifiers

PMID41458211
PMCPMC12741096

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.