ReviewFrontiers in neurology2025
Faith, fasting, and well-being: Emirates Neurology Society consensus guidelines on safe Ramadan fasting in Parkinson's disease.
Review in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Parkinson's disease in the United Arab Emirates (UAE): Emirates Neurology Society consensus guidelines.Frontiers in neurology · 2026Guideline
- Predictive validation of the repeated low-dose reserpine rodent model of parkinsonism.Experimental brain research · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by motor and non-motor symptoms. During Ramadan, fasting Muslims abstain from food, drink, and often medications between sunrise and sunset. Objective: To review the clinical considerations, therapeutic strategies, and cultural factors relevant to managing PD patients during Ramadan fasting, and to provide practical recommendations for neurologists and healthcare providers. Methods: This review synthesized existing guidelines (e.g., BIMA Ramadan Compendium), literature on drug pharmacokinetics during fasting, and clinical expertise from PD specialists in Middle Eastern and global Muslim populations. Discussions at a PD consensus meeting informed a stepwise algorithm for individualized care. Results: Pre-Ramadan risk assessment is essential, with stratification by disease stage. Early PD (Hoehn and Yahr stage 1-2) patients on monotherapy may fast safely with minimal adjustments, while moderate PD (Hoehn and Yahr stage 3) with multiple daily levodopa doses or combination therapy, requires consolidation of levodopa doses, addition of long-acting agents, and avoidance of dose stacking. Advanced PD patients who have troublesome motor/non-motor fluctuations and dyskinesias as well, and are taking medications multiple times per day are often unsuitable for fasting. Common complications include response fluctuations, dyskinesias, and sleep disturbances exacerbated by altered circadian rhythms. Long-acting dopaminergic therapies, including Dopamine Agonists (rotigotine patches and other extended-release (ER) oral agents), adjunctive agents (opicapone, rasagilline and safinamide), and Device-Aided Treatments (DAT; subcutaneous foslevodopa-foscarbidopa, subcutaneous continous subcutaneous apomorphine infusion, levodopa-carbidopa intestinal gel and deep brain stimulation) can help stabilize motor and non-motor fluctuations. Sleep hygiene measures and behavioral adjustments further support patient well-being. Cultural and spiritual motivations strongly influence adherence, requiring sensitive counseling and involvement of caregivers and religious leaders. Conclusion: Safe Ramadan fasting in PD requires comprehensive pre-Ramadan assessment, stage-specific therapeutic strategies, and proactive management of both motor and non-motor complications. Shared decision-making that integrates medical, psychological, and religious considerations is vital to optimize patient outcomes while respecting spiritual values.
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