ArticleFrontiers in neurology2025
Assessment of brain compliance in patients with migraine: use of non-invasive intracranial monitoring in outpatient clinics.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to characterize the morphology of the cerebral compliance monitoring curve in patients with primary headaches, specifically differentiating between migraine with aura and migraine without aura, using non-invasive intracranial monitoring. This study is innovative in that it applies Brain4Care® technology in an outpatient setting to differentiate migraine types, making a significant contribution to understanding the pathophysiology of headaches and thus improving clinical management strategies. A cross-sectional, prospective study was carried out with 50 patients seen at an outpatient clinic specializing in pain. Variables such as the P2/P1 ratio, time to peak (TTP), and the morphology of the cerebral compliance wave were assessed, as well as demographic and clinical factors. A high prevalence of altered P2/P1 ratio (P2 > P1) was observed in patients suffering from migraine with aura. Statistical analyses indicated significant associations between this ratio and factors such as age and the presence of symptoms at the time of the examination. The findings emphasize the importance of the P2/P1 ratio and TTP as indicators for differentiating primary headaches. A non-invasive intracranial monitoring offers valuable insights into brain dynamics, enabling more accurate diagnoses and personalized interventions in outpatient settings. Brain4Care® technology is emerging as a promising tool for the non-invasive monitoring of cerebral compliance, with the potential to revolutionize clinical management of migraines. Future studies should extend the validation of these findings and explore new applications for this technology in clinical practices.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.