ArticleAmerican journal of preventive cardiology2026
Impact of patient phenotype on the relationship between accelerometer-derived physical activity and cardiovascular events in atrial fibrillation.
Article in American journal of preventive cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Aims: Atrial fibrillation (AF) is a heterogeneous condition with varying comorbidity profiles, yet current physical activity guidelines do not differentiate between AF phenotypes. We examined the association between objectively measured moderate-to-vigorous physical activity (MVPA) and major adverse cardiovascular events (MACE) across different AF phenotypes. Methods: In a prospective cohort of 4858 adults with AF (mean age 63, 37 % female) from the UK Biobank, wrist-worn accelerometry quantified MVPA. Hierarchical clustering classified individuals into 'high' and 'low' risk clusters based on comorbidities. Activity patterns were also described by rhythm control treatment status. Cox-proportional hazards models assessed the association between MVPA and MACE across clusters, while Poisson regression identified notable MVPA thresholds. Results: The 'high-risk' cluster ( Conclusion: In this AF cohort, higher MVPA was associated with lower MACE incidence across different risk phenotypes and treatment statuses.
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