Evidence map›Paper›PMID 41457873›Full record

ReviewAnnals of medicine2026

Collaborative artificial intelligence for the diagnosis and management of acute ischemic stroke.

Zhiqiang Fan, Qian Chen, Wang Lu, Zhu Yao, Shijie Yang, Hongting Zhao, Hua Cao

Abstract readReview
In one paragraph

Review in Annals of medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Recent advances in diagnostic and therapeutic approaches for pulmonary enteric adenocarcinoma.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhiqiang FanDepartment of Cerebrovascular Disease, Gansu Provincial Hospital of TCM, Lanzhou, China.
Qian ChenResearch Center for Ubiquitous Computing System, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China.ORCID 0009-0002-2579-4380
Wang LuDepartment of Automation, Tsinghua University, Beijing, China.
Zhu YaoCollege of Biomedical Engineering & Instrument Science, Zhejiang University, Hangzhou, China.
Shijie YangThe First Clinical Medical College, Lanzhou University, Lanzhou, China.
Hongting ZhaoDepartment of Cerebrovascular Disease, Gansu Provincial Hospital of TCM, Lanzhou, China.
Hua CaoDepartment of Cerebrovascular Disease, Gansu Provincial Hospital of TCM, Lanzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute Ischemic Stroke (AIS) remains a critical global health challenge that requires continuous improvement in diagnostic strategies. Timely and accurate diagnosis is essential for effective reperfusion therapies such as intravenous thrombolysis and mechanical thrombectomy, whose clinical benefits rapidly diminish with treatment delays. Artificial Intelligence (AI) offers promising potential to enhance diagnostic accuracy and clinical decision-making in AIS. However, data fragmentation and strict privacy regulations limit the development of robust AI systems.

methodsWe analysed current challenges in developing AIS-related AI tools, particularly the limitations caused by restricted data sharing across healthcare institutions. The study highlights collaborative AI approaches, such as federated learning and privacy-preserving computation, which enable decentralised model training while maintaining patient confidentiality. Relevant literature and recent developments in clinical AI collaboration were reviewed.

resultsCollaborative AI enables multiple institutions to contribute to model training without exposing raw patient data. This approach improves data diversity, model generalizability, and fairness across healthcare settings. Evidence from multi-centre studies suggests that collaborative AI frameworks can produce more accurate and ethically compliant diagnostic models compared to isolated development efforts.

conclusionsCollaborative AI presents a transformative pathway for AIS management by balancing data utility and privacy protection. It supports the creation of trustworthy, scalable, and inclusive diagnostic systems. As healthcare systems increasingly adopt digital solutions, collaborative AI provides a foundation for equitable and privacy-conscious innovation in stroke care.

Indexed as

Artificial IntelligenceIschemic StrokeClinical Decision-MakingHumansThrombolytic TherapyAcute ischemic strokeartificial intelligencedeep learningfederated learningtrustworthy healthcare

Identifiers

PMID41457873
PMCPMC12777894

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.