SynthesisClinical and experimental dental research2025
Oral Health Interventions in Children With Autism Spectrum Disorder: A Systematic Review and Meta-Analysis of Interventional Studies.
Synthesis in Clinical and experimental dental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Oral Health Interventions in Children With Autism Spectrum Disorder: A Systematic Review and Meta-Analysis of Interventional Studies.Clinical and experimental dental research · 2025Pooled it
- Oral Health-Related Quality of Life and Its Determinants in Children and Adolescents with Autism Spectrum Disorder: A Scoping Review.Dentistry journal · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesChildren with autism spectrum disorder (ASD) exhibit a higher prevalence of oral health diseases. These oral health issues significantly impair quality of life and increase caregiver burden. Despite emerging interventions like specialized behavioral guidance and caregiver training, a comprehensive evaluation of their effectiveness remains absent. This systematic review and meta-analysis was designed to pool the effectiveness of Oral health interventions in children with ASD. MATERIALS AND
methodsIn this systematic review, some international databases, including PubMed, ISI/WOS, CENTRAL, and Scopus, were searched via appropriate keywords until January 1, 2025. All clinical trials that assessed the effect of interventions on oral health indices including Simplified Oral Hygiene Index (OHI-S), plaque index (PI), and gingival index (GI) without any language or time restrictions were included in the study. Search strategy process, screening, data extraction, and quality assessment were performed by two experts independently. Heterogeneity between studies was assessed using I
resultsOverall, 27 studies with 1918 participants were included in this study. Interventions are categorized into the educational (visual, verbal, booklet/leaflet) and procedural approaches. Random effect meta-analysis showed significant improvements for PI (SMD = -0.73, 95% CI: [-1.02 to -0.44]) and OHI-S (SMD = -1.44, 95% CI: [-2.79 to -0.08]), with video interventions notably effective for PI (SMD = -0.69, 95% CI: [-1.2 to -0.14]). The GI index also improved (SMD = -0.74, 95% CI: [-1.34 to -0.14]).
conclusionsVisual pedagogy, particularly videos, and parental involvement significantly improved oral health in children with ASD. Video-based interventions should be added to traditional methods such as verbal or picture-based approaches to improve oral health interventions in ASD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.