Evidence map›Paper›PMID 41457207›Full record

ArticleBMC cardiovascular disorders2025

Anxiety in patients referred for elective coronary angiography: a prospective cohort study.

Anja Kokalj Palandacic, Saša Ucman, Dragan Kovacic, Brigita Novak Sarotar, Mitja Lainscak

2 registry-linked trialsAbstract read
In one paragraph

Article in BMC cardiovascular disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02804009 unknown statusnot on this map

Evaluating and Predicting Anxiety in Patients Undergoing Elective Coronary Angiography

TypeobservationalSponsorGeneral and Teaching Hospital CeljeRan2015 to 2017Enrolled350ConditionsAnxiety
NCT07723521 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Effect of Stress Ball Application During Coronary Angiography on Anxiety, Procedure-related Fear, Physiological Parameters, and Comfort: a Randomized Controlled Trial

TypeinterventionalSponsorTarsus UniversityRan2026 to 2027Enrolled64ConditionsStress BallArmsStress ball
3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Anja Kokalj PalandacicUniversity Psychiatric Clinic Ljubljana, Chengdujska 45, Ljubljana, 1000, Slovenia. anja.kokalj@psih-klinika.si.
Saša UcmanUniversity Psychiatric Clinic Ljubljana, Chengdujska 45, Ljubljana, 1000, Slovenia.
Dragan KovacicDepartment of Cardiology, General Hospital Celje, Oblakova ul. 5, Celje, 3000, Slovenia.
Brigita Novak Sarotar *University Psychiatric Clinic Ljubljana, Chengdujska 45, Ljubljana, 1000, Slovenia.
Mitja Lainscak *Faculty of Medicine, University of Ljubljana, Vrazov trg 2, Ljubljana, 1000, Slovenia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMedical procedures have the potential to elicit feelings of anxiety, which have been associated with reduced health-related quality of life and cardiac dysfunction. The prevalence of anxiety in patients referred for elective coronary angiography (CA) ranges from 24% to 72%. Anxiety, in combination with coping, was rarely assessed apart from depression in these patients. The aims of this study were to determine the prevalence of anxiety, assess its correlation with coping traits, and with elective CA findings in non-depressed patients.

methodsThis was a single-center, prospective cohort study. Anxiety was evaluated: two weeks before, on the day of CA, 24-hours post CA, and one month post CA. Psychological parameters were determined using self-administered questionnaires and anxiety was analyzed on those without depressive symptoms. The association between anxiety and psychological variables was assessed by multiple linear regression and by linear mixed effect model.

resultsOut of 393 patients screened for depression and anxiety, 259 non-depressed patients (age 65 years, 36% women) were analyzed. Anxiety was present in 91/259 (35%) of patients. Avoidance-oriented coping was a significant predictor of higher trait anxiety (p < 0.001) and lower state anxiety 24-hours post CA. CA indicated no intervention in 183 patients (71%), while revascularization, either percutaneous (49 patients, 19%) or surgical (27 patients, 10%), was performed in the remaining patients. Anxiety decreased between the baseline and all subsequent time points (p < 0.001) in all groups.

conclusionsMore than one third of non-depressed patients experience clinically significant anxiety before CA. Avoidance-oriented coping has a significant impact on anxiety. The findings of our study suggest the routine screening for anxiety and coping strategies prior to elective CA might be helpful to identify those individuals who are in need for additional psychological interventions. CLINICAL TRIAL NUMBER: The study was registered at ClinicalTrials.gov (NCT02804009).

Indexed as

AnxietyCoronary AngiographyCoronary Artery DiseaseReferral and ConsultationAdaptation, PsychologicalAgedFemaleHumansMaleMiddle AgedPredictive Value of TestsPrevalenceProspective StudiesRisk FactorsTime FactorsAnxietyAvoidance-oriented copingCoronary angiographyCoronary artery bypass graft surgeryPercutaneous coronary intervention

Identifiers

PMID41457207
PMCPMC12859959

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.