ArticleCardiovascular and interventional radiology2026
Transfissural Route: A Safe Pathway for Medical Adhesive Localization of Challenging Pulmonary Nodules.
Article in Cardiovascular and interventional radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Optical Navigation Robot-Assisted versus Conventional CT-Guided Localization of Pulmonary Nodules: A Comparison of Efficacy and Analysis of Complication Predictors.Cardiovascular and interventional radiology · 2026Article
- Commentary on Transfissural Route: A Safe Pathway for Medical Adhesive Localization of Challenging Pulmonary Nodules.Cardiovascular and interventional radiology · 2026Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate the feasibility and safety of the transfissural route for computed tomography (CT)-guided preoperative localization with medical adhesive for video-assisted thoracoscopic surgery (VATS) resection of challenging pulmonary nodules. MATERIALS AND
methodsThis retrospective study analyzed patients who underwent CT-guided medical adhesive before VATS resection between January 2019 and August 2024. Patients were categorized into transfissural (Group T, n = 31) and conventional (Group C, n = 513) route groups. Propensity score matching (1:4) was performed to control for baseline variables, resulting in 27 matched patients in Group T and 69 in Group C. Localization and surgical outcomes were compared between the two groups. Multiple linear regression analysis was performed to verify the independent association with post-localization pain score.
resultsIn the overall cohort, both groups achieved 100% localization success. No significant differences were observed in initial failure rate, resection success, localization time, or complication rates (including hemorrhage and pneumothorax) between groups, both before and after matching (all P > 0.05). However, Group T was associated with significantly higher pain scores both before (median 4 vs. 3, P < 0.001) and after matching (median 4 vs. 3, P = 0.008), despite comparable morphine use (P = 0.947 post-matching). Multiple linear regression further confirmed the transfissural route as an independent factor significantly associated with increased post-localization pain (P < 0.001).
conclusionThe transfissural route for CT-guided medical adhesive localization is a technically feasible and safe strategy for challenging pulmonary nodules. However, the increased pain score should be considered. LEVEL OF EVIDENCE 3: Non-controlled retrospective cohort study.
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