Evidence map›Paper›PMID 41457157›Full record

ArticleScientific reports2025

Calcium-dependent activation of TREK-1 and TREK-2 background potassium channels by calcineurin.

Dóra Baukál, Enikő Pergel, Dorina Debreczeni, Ármin Horváth, Dániel J Tóth, Panna T Takács, Gábor Czirják

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dóra BaukálDepartment of Physiology, Semmelweis University, P. O. Box 2, Budapest, 1428, Hungary.
Enikő PergelDepartment of Physiology, Semmelweis University, P. O. Box 2, Budapest, 1428, Hungary.
Dorina DebreczeniDepartment of Physiology, Semmelweis University, P. O. Box 2, Budapest, 1428, Hungary.
Ármin HorváthDepartment of Physiology, Semmelweis University, P. O. Box 2, Budapest, 1428, Hungary.
Dániel J TóthDepartment of Physiology, Semmelweis University, P. O. Box 2, Budapest, 1428, Hungary.
Panna T TakácsDepartment of Physiology, Semmelweis University, P. O. Box 2, Budapest, 1428, Hungary.
Gábor CzirjákDepartment of Physiology, Semmelweis University, P. O. Box 2, Budapest, 1428, Hungary. czirjak.gabor@semmelweis.hu.

Funding

National Academy of Scientist Education Program of the National Biomedical Foundation, under the sponsorship of the Hungarian Ministry of Culture and Innovation FEIF/646-4/2021-ITM_SZERZNational Research, Development and Innovation Office K-127988
6 · The paper itself

Abstract

TREK-1 (K

Indexed as

CalcineurinCalciumPotassium Channels, Tandem Pore DomainA Kinase Anchor ProteinsAnimalsHumansIonomycinOocytesPhosphorylationTacrolimusXenopus laevisA Kinase Anchor ProteinsCalcineurinCalciumIonomycinpotassium channel protein TREK-1Potassium Channels, Tandem Pore DomainTacrolimusK2P10K2P2KCNK10KCNK2PP2BTREK1TREK2Xenopus oocyte

Identifiers

PMID41457157
PMCPMC12855957

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.