Evidence map›Paper›PMID 41457104›Full record

ArticleNPJ digital medicine2025

ScarElastic: continuous elasticity field modeling for myocardial scar delineation in LGE-CMR.

Rongjun Zou, Yugui Li, Na Zhou, Xuechun Guan, Guanmou Li, Donghao Xie, Jingyu Bo, Siya Li, Min Wu, Jinhai Deng and 2 more

Abstract read
In one paragraph

Article in NPJ digital medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rongjun Zou *The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Hospital of Chinese Medicine, State Key Laboratory of Traditional Chinese Medicine Syndrome, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Yugui Li *Department of Cardiovascular Surgery Ward, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, China.
Na Zhou *Heart Center, Guangdong Provincial Key Laboratory of Research in Structural Birth Defect Disease, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China.
Xuechun GuanDepartment of Radiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, China.
Guanmou LiThe Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Hospital of Chinese Medicine, State Key Laboratory of Traditional Chinese Medicine Syndrome, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Donghao XieHeart Center, Guangdong Provincial Key Laboratory of Research in Structural Birth Defect Disease, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China.
Jingyu BoThe Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Hospital of Chinese Medicine, State Key Laboratory of Traditional Chinese Medicine Syndrome, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Siya LiCAS Blue Bay Cloud Technology (Guangdong) Co., Ltd., Shenzhen, Guangdong, China.
Min WuGuangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China. wumin0011@gdph.org.cn.
Jinhai DengRichard Dimbleby Department of Cancer Research, Comprehensive Cancer Centre, King's College London, London, UK. jinhaideng_kcl@163.com.
Xiaoping FanThe Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Hospital of Chinese Medicine, State Key Laboratory of Traditional Chinese Medicine Syndrome, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China. fanxiaoping@gzucm.edu.cn.
Cheng LuoDepartment of Cardiovascular Surgery Ward, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, China. drluocheng@163.com.

Funding

Basic Clinical Collaborative Innovation Program of Guangdong Provincial Hospital of Traditional Chinese Medicine and School of Biomedical Sciences, The Chinese University of Hong Kong No. YN2024HK01Excellent Young Talents Program of Guangdong Provincial Hospital of Traditional Chinese Medicine No. SZ2024QN05Guangdong Province Basic and Applied Basic Research Fund Project No. 2025A1515012690Guangdong Provincial Key Laboratory of Research on Emergency in TCM No. 2023B1212060062Guangxi Natural Science Foundation Grant Nos. 2025GXNSFAA069056 and AB24010153Guangzhou Science and Technology Bureau Project No.2024A03J1165National Administration of Traditional Chinese Medicine Research Project No. 0102023703National Natural Science Foundation of China NO.82374240Project of the State Key Laboratory of Dampness Syndrome of Traditional Chinese Medicine jointly established by the province and the ministry No.SZ2022KF10Research Project of Guangdong Provincial Bureau of Traditional Chinese Medicine No.20241120Scientific Research Initiation Project of Guangdong Provincial Hospital of Traditional Chinese Medicine No.2021KT1709The Basic and Applied Basic Research Project of Guangzhou Municiple Science and Technology Bureau No.2025A03J4265
6 · The paper itself

Abstract

Late gadolinium-enhanced cardiac magnetic resonance (LGE-CMR) imaging is a crucial modality for identifying myocardial scar, yet current binary segmentation approaches often fail to capture the continuous and heterogeneous nature of fibrosis. In this study, we propose ScarElastic, a novel framework that models scar as a continuous elasticity field, enabling the preservation of myocardial wall topology and more faithful delineation of diffuse or patchy lesions. Across three public benchmarks (STACOM-LGE 2018, MyoPS 2020, and MS-CMRSeg 2019), ScarElastic consistently outperformed state-of-the-art methods, achieving up to +3.1% Dice improvement, -1.8 mm reduction in HD95, and a +0.06 gain in structural continuity score. These gains were particularly pronounced in hypertrophic cardiomyopathy (HCM) cases with complex scar morphology. Beyond quantitative accuracy, the elasticity field provides interpretable maps that correlate with clinical indices such as scar burden and transmural extent, suggesting strong potential for integration into clinical workflows.

Identifiers

PMID41457104
PMCPMC12764763

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.