ArticleJournal of applied clinical medical physics2026
Impact of tumor motion on target delineation and dose calculation accuracy using rapid-acquisition HyperSight CBCT in online adaptive radiotherapy.
Article in Journal of applied clinical medical physics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- A clinical evaluation of HyperSight CBCT enhanced offline adaptive breast radiotherapy.Frontiers in oncology · 2026Article
- Impact of tumor motion on target delineation and dose calculation accuracy using rapid-acquisition HyperSight CBCT in online adaptive radiotherapy.Journal of applied clinical medical physics · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHyperSight CBCT offers rapid image acquisition and enhanced image quality, supporting its integration into online adaptive radiotherapy (OART). However, its performance under respiratory-induced tumor motion requires further evaluation. PURPOSE: This study evaluates the feasibility of using rapid-acquisition HyperSight CBCT for internal target volume (ITV) delineation and dose calculation in the setting of respiratory motion, with implications for OART workflows.
methodsA dynamic thoracic phantom simulating superior-inferior tumor motion (5-25 mm amplitude from the motion center, 6-second cycle time) was imaged using Varian's HyperSight CBCT on the Ethos platform. Four reconstruction algorithms were evaluated: filtered back projection (FDK), iterative CBCT (iCBCT), iCBCT with Acuros, and metal artifact reduction (MAR). Experiments included variation of cycle times (4, 6, and 8 s), breathing patterns (Cos
resultsFor the Cos
conclusionsHyperSight CBCT is feasible for OART in patients with limited respiratory motion, regular breathing pattern and short breathing cycle time. For larger excursions, slow scans or motion management strategies may be required to ensure accurate target delineation and dose calculation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.