Evidence map›Paper›PMID 41456542›Full record

ArticleInternational dental journal2026

Effect of Topical Fluoride Application Temperature on Recharge and Rerelease in Different Restorative Materials.

Ji-Eun Kim, Ji-Yeon Hong, Kwang-Mahn Kim, Jae-Sung Kwon

Abstract read
In one paragraph

Article in International dental journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Ji-Eun KimDepartment and Research Institute of Dental Biomaterials and Bioengineering, Yonsei University College of Dentistry, Seoul, Republic of Korea.
Ji-Yeon HongDepartment and Research Institute of Dental Biomaterials and Bioengineering, Yonsei University College of Dentistry, Seoul, Republic of Korea; BK21 FOUR Project, Yonsei University College of Dentistry, Seoul, Republic of Korea.
Kwang-Mahn KimDepartment and Research Institute of Dental Biomaterials and Bioengineering, Yonsei University College of Dentistry, Seoul, Republic of Korea.
Jae-Sung KwonDepartment and Research Institute of Dental Biomaterials and Bioengineering, Yonsei University College of Dentistry, Seoul, Republic of Korea; BK21 FOUR Project, Yonsei University College of Dentistry, Seoul, Republic of Korea. Electronic address: jkwon@yuhs.ac.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

INTRODUCTION AND

aimsThis study aimed to evaluate the influence of topical fluoride application temperature on the recharge and rerelease behaviour of three fluoride-containing restorative materials treated with 1.23% acidulated phosphate fluoride (APF) gel and 8% stannous fluoride (SnF₂).

methodsSpecimens of an alkasite-restorative material (Cention N), a resin-modified glass ionomer (Fuji II LC), and a conventional glass ionomer (Fuji IX GP) were prepared (n = 32 per material; n = 8 for each combination of fluoride agent and temperature). After an initial 64-day fluoride release phase in deionized water, samples were recharged with APF gel or SnF₂ at room temperature (23 ± 2°C) or high temperature (HT) (55 ± 2°C) for 4 minutes. Subsequent fluoride rerelease was measured for 32 days. Physicochemical properties of fluoride agents, including viscosity, temperature, and pH, were analysed. Elemental mapping of fluoride and tin distribution was performed using scanning electron microscope-energy-dispersive X-ray spectroscopy.

resultsAll restorative materials initially showed rapid fluoride release that decreased over 64 days. After topical application, cumulative fluoride rerelease was significantly higher under HT than room temperature across all groups (P < .05), particularly with APF gel. RMGI demonstrated the greatest fluoride rerelease, while CGI showed the highest initial release. Scanning electron microscope-energy-dispersive X-ray spectroscopy revealed higher fluoride content at HT across all materials in both surface and cross-sectional analyses, regardless of the fluoride agent used. Tin distribution was detected only in SnF₂-treated groups.

conclusionElevated application temperature significantly improves the fluoride recharge and sustained release capacity of restorative materials, with outcomes depending on the fluoride agent and material type. CLINICAL RELEVANCE: Applying topical fluoride at higher temperatures may enhance its anticariogenic efficacy by promoting greater fluoride uptake and prolonged release from restorative materials. These findings highlight the importance of considering application conditions when optimizing preventive protocols in clinical practice.

Indexed as

Cariostatic AgentsDental MaterialsFluorides, TopicalGlass Ionomer CementsTin FluoridesAcidulated Phosphate FluorideAcrylic ResinsFluoridesFluoride TreatmentHydrogen-Ion ConcentrationMaterials TestingMicroscopy, Electron, ScanningResins, SyntheticTemperatureViscosityAcidulated Phosphate FluorideAcrylic ResinsCariostatic AgentsDental MaterialsFluoridesFluorides, TopicalFuji II LC cementfuji IXGlass Ionomer CementsResins, SyntheticTin FluoridesAcidulated phosphate fluoride gelFluoride applicationFluoride-containing restorative materialFluoride ion releaseFluoride uptakeStannous fluoride

Identifiers

PMID41456542
PMCPMC12796922

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.