Evidence map›Paper›PMID 41456253›Full record

ArticleAnalytical and bioanalytical chemistry2026

Differentiation of steroid isomers via derivatization and electron-activated dissociation tandem mass spectrometry.

Tian Tian, Haidong Cheng, Xue Zhao

Abstract read
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In one paragraph

Article in Analytical and bioanalytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tian TianCollege of Chemistry and Chemical Engineering, Inner Mongolia University, Hohhot, 010021, China.
Haidong ChengDepartment of Gastrointestinal Surgery, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, 010059, Inner Mongolia, China. 763175936@qq.com.
Xue ZhaoCollege of Chemistry and Chemical Engineering, Inner Mongolia University, Hohhot, 010021, China. x-zhao@imu.edu.cn.ORCID http://orcid.org/0009-0001-8686-2773

Funding

National Natural Science Foundation of China 22304088Natural Science Foundation of Inner Mongolia Autonomous Region 2023QN02002
6 · The paper itself

Abstract

Steroids are a class of lipids sharing a cyclopentanoperhydrophenanthrene skeleton, and they play a critical role in the diagnosis and monitoring of numerous endocrine pathologies. However, steroid analysis faces unique challenges, primarily due to their low biological concentrations, poor ionization efficiencies, and high structural similarities-especially among isomers. Herein, we describe a novel analytical strategy that combines Girard's P (GirP) derivatization of steroids with electron-activated dissociation (EAD) in MS

Indexed as

SteroidsTandem Mass SpectrometryAnimalsIsomerismMaleMiceSteroidsElectron activated dissociationGirard’s P derivatizationSteroidsTandem mass spectrometry

Identifiers

PMID41456253

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.