Evidence map›Paper›PMID 41456200›Full record

ArticleExperimental physiology2026

Cardiovascular, respiratory and splenic responses to rebreathing and apnoea during exercise.

Theodore Dotevall, Maja Persson, Bodil Sjögreen, Mats H Linér, Angelica Lodin-Sundström, Johan P A Andersson

Abstract read
In one paragraph

Article in Experimental physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Theodore DotevallDepartment of Experimental Medical Science, Lund University, Lund, Sweden.ORCID https://orcid.org/0009-0002-7777-0460
Maja PerssonDepartment of Experimental Medical Science, Lund University, Lund, Sweden.
Bodil SjögreenDepartment of Biology, Lund University, Lund, Sweden.ORCID https://orcid.org/0009-0000-1326-5102
Mats H LinérDepartment of Experimental Medical Science, Lund University, Lund, Sweden.
Angelica Lodin-SundströmDepartment of Experimental Medical Science, Lund University, Lund, Sweden.ORCID https://orcid.org/0000-0002-2036-8983
Johan P A AnderssonDepartment of Experimental Medical Science, Lund University, Lund, Sweden.ORCID https://orcid.org/0000-0002-4487-6456

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated integrative physiological responses to eupnoeic exercise (EX), rebreathing exercise (RB), dynamic apnoea (DA) and dynamic apnoea with cold-water face immersion (DAFI) in 20 healthy participants. Trials involved non-steady-state cycle exercise at 60 W for an average duration of 66 s. With increases in heart rate and stroke volume, EX and RB increased cardiac output compared with baseline (mean [SD] EX +47 [13]%, RB +43 [15]%). During DA and DAFI, the increase in cardiac output was attenuated (DA +26 [23]%, DAFI +14 [21]%). EX and RB elicited reductions in total peripheral resistance (EX -37 [7]%, RB -23 [15]%). This reduction was absent during apnoeas (DA +3 [31]%, DAFI +15 [40]%). Pulmonary oxygen uptake was the lowest during DAFI. At the end of hypoxic trials, end-tidal partial pressures of O

Indexed as

ApneaExerciseSpleenAdultCardiac OutputFemaleHeart RateHumansImmersionMaleOxygen ConsumptionOxygen SaturationStroke VolumeVascular ResistanceYoung Adultapnoeaexerciserebreathing

Identifiers

PMID41456200
PMCPMC13140216

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.