Evidence map›Paper›PMID 41455983›Full record

ArticleBMC surgery2025

Development and validation of a preoperative predictive scoring system for esophageal perforation induced by fishbones.

Jie Xu, Bin He, Yunfu Feng, Luojie Liu, Jingjie Zhou

Abstract readMulticenter StudyValidation Study
In one paragraph

Article in BMC surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Jie Xu *Department of Gastroenterology, The Affiliated Zhangjiagang Hospital of Soochow University, Suzhou, China.
Bin He *Department of Gastroenterology, The Affiliated Zhangjiagang Hospital of Soochow University, Suzhou, China.
Yunfu FengDepartment of Endoscopy Center, The First People's Hospital of Kunshan, Suzhou, China.
Luojie LiuDepartment of Gastroenterology, Changshu Hospital Affiliated to Soochow University, Suzhou, China. luojieliu@126.com.
Jingjie ZhouDepartment of Gastroenterology, Changshu Hospital Affiliated to Soochow University, Suzhou, China. 249057302@qq.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFishbones are the most common esophageal foreign bodies, with perforation representing their most severe complication. However, reliable tools to preoperatively predict perforation risk are lacking. This study aimed to develop and validate a practical scoring system for this purpose.

methodsA multi-center retrospective study enrolled 1,248 patients with fishbone-related esophageal foreign bodies, randomly divided into training (n = 512), internal validation (n = 220), and external validation cohorts (n = 516). Univariate and multivariate logistic regression identified independent risk factors for perforation. A scoring system was constructed by weighting regression coefficients. Performance was assessed using the area under the curve (AUC), sensitivity, specificity, accuracy, and predictive values.

resultsEsophageal perforation occurred in 12.7% (159/1,248) of patients. Three independent predictors were identified: fishbone length ≥ 2.0 cm (2 points), lodgment duration ≥ 24 h (1 point), and forced swallowing (1 point). The system demonstrated strong discrimination, with AUCs of 0.863 (internal) and 0.829 (external). Risk stratification revealed perforation rates of 9.9% (low-risk: 0–2 points), 83.3% (intermediate-risk: 3 points), and 100.0% (high-risk: 4 points) in internal validation, and 8.6%, 63.6%, and 100.0% in external validation.

conclusionThis scoring system, incorporating fishbone length, lodgment duration, and forced swallowing, shows promising performance in predicting esophageal perforation risk and may assist in preoperative risk stratification. Further validation in broader populations is warranted to confirm its clinical utility.

Indexed as

Esophageal PerforationEsophagusForeign BodiesSeafoodAdultAgedAnimalsBone and BonesFemaleFishesHumansMaleMiddle AgedPredictive Value of TestsRetrospective StudiesRisk AssessmentEsophageal perforationFishboneScoring system

Identifiers

PMID41455983
PMCPMC12853955

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.