Evidence map›Paper›PMID 41455897›Full record

ArticleBMC gastroenterology2025

WeChat-based manual enhanced guidance in patients with Helicobacter pylori infection.

Xiaoye Shi, Zhe Li, Zhenhua Tong, Chun Ye, Wentao Xu, Hongyu Li, Xingshun Qi

Abstract read
In one paragraph

Article in BMC gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Xiaoye Shi *Department of Gastroenterology, General Hospital of Northern Theater Command (formerly General Hospital of Shenyang Military Area), No. 83 Wenhua Road, Shenyang, Liaoning Province, 110840, China.
Zhe Li *Department of Gastroenterology, General Hospital of Northern Theater Command (formerly General Hospital of Shenyang Military Area), No. 83 Wenhua Road, Shenyang, Liaoning Province, 110840, China.
Zhenhua Tong *Section of Medical Service, General Hospital of Northern Theater Command, Shenyang, China.
Chun Ye *Department of General Surgery, General Hospital of Northern Theater Command (formerly General Hospital of Shenyang Military Area), Shenyang, China.
Wentao XuDepartment of Gastroenterology, General Hospital of Northern Theater Command (formerly General Hospital of Shenyang Military Area), No. 83 Wenhua Road, Shenyang, Liaoning Province, 110840, China.
Hongyu LiDepartment of Gastroenterology, General Hospital of Northern Theater Command (formerly General Hospital of Shenyang Military Area), No. 83 Wenhua Road, Shenyang, Liaoning Province, 110840, China.
Xingshun QiDepartment of Gastroenterology, General Hospital of Northern Theater Command (formerly General Hospital of Shenyang Military Area), No. 83 Wenhua Road, Shenyang, Liaoning Province, 110840, China. xingshunqi@126.com.

Funding

Science and Technology Plan Project of Liaoning Province 2022JH2/101500033
6 · The paper itself

Abstract

backgroundPatients' adherence is important for successful Helicobacter pylori (H. pylori) eradication, and may be improved by WeChat, a popular social networking platform. This study aimed to evaluate patients' adherence, successful H. pylori eradication, and clinical remission under the WeChat-based enhanced guidance.

methodsNinety-nine patients with H. pylori infection, who were treated by a 14-day standard bismuth-containing quadruple therapy (BQT) and received the WeChat-based enhanced guidance, were retrospectively included. Multivariate logistic regression analysis was performed to identify independent predictors of patients' adherence and H. pylori eradication. Odds ratios (ORs) were calculated.

resultsThe rates of good medication adherence, good re-examination adherence, successful H. pylori eradication, and clinical remission were 97.0%, 83.8%, 89.2%, and 89.5%, respectively. Patients with poor re-examination adherence had significantly lower proportions of individual dining (13.3% versus 50.6%, P=0.008) and no smoking during treatment (66.7% versus 92.8%, P=0.012) than those with good re-examination adherence. Both individual dining (OR=0.182, P=0.035) and no smoking during treatment (OR=0.210, P=0.031) were independently associated with good re-examination adherence. Patients with H. pylori eradication failure had significantly higher proportions of poor medication adherence (22.2% versus 1.4%, P=0.030) and living in rural area (44.4% versus 8.1%, P=0.009) than those with H. pylori eradication success. Both poor medication adherence (OR=20.366, P=0.031) and living in rural area (OR=8.944, P=0.010) were independently associated with H. pylori eradication failure.

conclusionThere is good medication adherence with satisfactory H. pylori eradication and clinical remission under the WeChat-based enhanced guidance. How to improve re-examination adherence should be further explored.

Indexed as

Anti-Bacterial AgentsHelicobacter InfectionsHelicobacter pyloriMedication AdherenceAdultAgedBismuthDrug Therapy, CombinationFemaleHumansMaleMiddle AgedProton Pump InhibitorsRemission InductionRetrospective StudiesAnti-Bacterial AgentsBismuthProton Pump InhibitorsAdherenceClinical remissionEnhanced guidanceEradicationHelicobacter pyloriWeChat

Identifiers

PMID41455897
PMCPMC12859890

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.