Evidence map›Paper›PMID 41455823›Full record

ArticleNPJ digital medicine2025

Multimodal deep learning for cancer prognosis prediction with clinical information prompts integration.

Jiaxin Hou, Ranran Zhang, Yaoqin Xie, Chao Li, Wenjian Qin

Abstract read
In one paragraph

Article in NPJ digital medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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  5. Multimodal AI in precision medicine: linking omics, imaging and clinical decisions.American journal of clinical and experimental immunology · 2026
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jiaxin HouShenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Ranran ZhangShenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Yaoqin XieShenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Chao LiDepartment of Applied Mathematics & Theoretical Physics, University of Cambridge, Cambridge, UK.
Wenjian QinShenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China. wj.qin@siat.ac.cn.

Funding

National Natural Science Foundation of China 62271475Shenzhen-Hong Kong Joint Lab on Intelligence Computational Analysis for Tumor Imaging E3G111Youth Innovation Promotion Association CAS 2022365
6 · The paper itself

Abstract

Survival prediction is crucial for guiding cancer treatment and evaluating therapeutic efficacy. However, tumor heterogeneity presents challenges of accurate prognosis. Multimodal learning, which integrates data from imaging, genomics, and clinical records, offers a promising approach for this complex task. While recent studies mainly focus on imaging and genomic data, clinical information, which reflecting patients' overall health, remains underutilized due to its discrete, sparse, and low-dimensional characteristics. We propose SurvPGC, an integrated model combining pathology images, genomic data and clinical records for cancer prognosis. Clinical information is transformed into high-dimensional vectors using text templates and foundation models, enabling their integration through a cross-attention module. Validation on three datasets of The Cancer Genome Atlas demonstrated that the model effectively captures modality-specific features, with attention visualization revealing distinct focus areas across data types. This highlights the importance of incorporating diverse information sources for improved survival prediction.

Identifiers

PMID41455823
PMCPMC12830675

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.