Evidence map›Paper›PMID 41455216›Full record

ArticlePoultry science2026

Comparative chromatin accessibility and transcriptome analyses identify key energy metabolism genes for hypoxia adaptation in embryos of Tibetan chickens.

Xing Guo, Bo Zhang, Zihan Chen, Xuejiao Chen, Chuchu Zhang, Wei Wei, Wendi Ma, Jingran Jiao, Hao Zhang, Mingshan Wang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Poultry science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xing GuoCollege of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Bo ZhangNational Engineering Laboratory for Livestock and Poultry Breeding, Beijing Key Laboratory of Animal Genetic Engineering, China Agricultural University, Beijing 100193, China.
Zihan ChenCollege of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Xuejiao ChenNational Engineering Laboratory for Livestock and Poultry Breeding, Beijing Key Laboratory of Animal Genetic Engineering, China Agricultural University, Beijing 100193, China.
Chuchu ZhangCollege of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Wei WeiCollege of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Wendi MaState Key Laboratory of Genetic Resources and Evolution and Yunnan Laboratory of Molecular Biology of Domestic Animals, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China.
Jingran JiaoCollege of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Hao ZhangNational Engineering Laboratory for Livestock and Poultry Breeding, Beijing Key Laboratory of Animal Genetic Engineering, China Agricultural University, Beijing 100193, China.
Mingshan WangState Key Laboratory of Genetic Resources and Evolution and Yunnan Laboratory of Molecular Biology of Domestic Animals, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China.
Runshen JiangCollege of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China. Electronic address: jiangrunshen@ahau.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tibetan chickens have evolved a unique energy metabolism that enables them to survive in high-altitude environments characterized by hypoxia. However, the genetic basis of this trait remains unclear. In this study, eggs from Tibetan and Leghorn chickens were incubated in hypoxic conditions (13 % O

Indexed as

Adaptation, PhysiologicalAvian ProteinsChickensEnergy MetabolismHypoxiaTranscriptomeAltitudeAnimalsChick EmbryoGene Expression ProfilingTibetAvian ProteinsATAC-seqEmbryo liverHypoxia adaptationRNA-seqTibetan chickens

Identifiers

PMID41455216
PMCPMC12950395

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.