Evidence map›Paper›PMID 41455076›Full record

ArticleNeuroscience bulletin2026

Characteristics and Cell Lineage Tracing of Neurod1-Cre and Neurod1-iCreER Mice Targeting Cochlear Neurons.

Zhiji Chen, Xiaoqing Zhou, Ting Yang, Xuelai Liu, Juhong Zhang, Menglong Feng, Shaojing Kuang, Wei Yuan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuroscience bulletin, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhiji ChenDepartment of Otorhinolaryngology Head and Neck Surgery, Chongqing General Hospital, Chongqing University, Chongqing, 401147, China.ORCID http://orcid.org/0000-0002-9097-2721
Xiaoqing ZhouDepartment of Otorhinolaryngology Head and Neck Surgery, Chongqing General Hospital, Chongqing University, Chongqing, 401147, China.ORCID http://orcid.org/0000-0003-2356-9518
Ting YangDepartment of Otorhinolaryngology Head and Neck Surgery, Chongqing General Hospital, Chongqing University, Chongqing, 401147, China.ORCID http://orcid.org/0000-0002-7835-3899
Xuelai LiuDepartment of Otorhinolaryngology Head and Neck Surgery, Chongqing General Hospital, Chongqing University, Chongqing, 401147, China.ORCID http://orcid.org/0000-0003-2889-9890
Juhong ZhangDepartment of Otorhinolaryngology Head and Neck Surgery, Chongqing General Hospital, Chongqing University, Chongqing, 401147, China.ORCID http://orcid.org/0009-0009-2506-2869
Menglong FengDepartment of Otorhinolaryngology Head and Neck Surgery, Chongqing General Hospital, Chongqing University, Chongqing, 401147, China.ORCID http://orcid.org/0000-0002-6918-2442
Shaojing KuangDepartment of Otorhinolaryngology Head and Neck Surgery, Chongqing General Hospital, Chongqing University, Chongqing, 401147, China.ORCID http://orcid.org/0000-0001-5109-237X
Wei YuanDepartment of Otorhinolaryngology Head and Neck Surgery, Chongqing General Hospital, Chongqing University, Chongqing, 401147, China. weiyuan175@sina.com.ORCID http://orcid.org/0009-0007-5255-3693

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The basic helix-loop-helix transcription factors, Neurog1 and Neurod1, orchestrate spiral ganglion neuron (SGN) differentiation in the embryonic cochlea. Their knockout leads to profound SGN and hair cell (HC) loss, cochlear truncation, and hearing impairment. To investigate SGN diversification and lineage origins, we generated three knock-in mouse strains: Neurod1-Cre, Neurod1-iCreER, and Neurog1-iCreER. In Neurod1-Cre; Rosa26-LSL-tdTomato (Ai9) mice, in addition to SGNs, tdTomato

Indexed as

Basic Helix-Loop-Helix ProteinsCell LineageCochleaNeuronsSpiral GanglionAnimalsFemaleHair Cells, AuditoryIntegrasesMiceMice, TransgenicNerve Tissue ProteinsTamoxifenBasic Helix-Loop-Helix ProteinsCre recombinaseIntegrasesNerve Tissue ProteinsNeurod1 protein, mouseNeurog1 protein, mouseTamoxifenCochleaMouse modelNeurod1Neurog1Spiral ganglion neuron

Identifiers

PMID41455076
PMCPMC13424057

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.