Evidence map›Paper›PMID 41455054›Full record

ReviewNeuropsychology review2025

Memory Test Performance of People with Subjective Cognitive Decline Recruited From Different Settings: A Systematic Review and Meta-analysis.

Katie A Peterson, Adrian Leddy, Fiona Ellis, Richard Meiser-Stedman, Michael Hornberger

Abstract readReview
PubMed Publisher
In one paragraph

Review in Neuropsychology review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Development and Validation of a Predictive Model for Identification of Cognitive Impairment Risk in Older Adults with Subjective Cognitive Decline:A Longitudinal Study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Katie A PetersonDepartment of Clinical Psychology and Psychological Therapies, Norwich Medical School, University of East Anglia, Norwich, UK.
Adrian LeddyDepartment of Clinical Psychology and Psychological Therapies, Norwich Medical School, University of East Anglia, Norwich, UK.
Fiona EllisDepartment of Clinical Psychology and Psychological Therapies, Norwich Medical School, University of East Anglia, Norwich, UK.
Richard Meiser-StedmanDepartment of Clinical Psychology and Psychological Therapies, Norwich Medical School, University of East Anglia, Norwich, UK.
Michael HornbergerClinical Neurosciences, Department for Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK. M.Hornberger@soton.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Subjective cognitive decline (SCD) is defined as self-experienced cognitive decline without objective impairment on standardised tests. Research suggests SCD may show subtle impairment on detailed neuropsychological assessment and might therefore indicate the earliest stage of neurodegeneration. This review (PROSPERO: CRD42023382096) seeks to determine whether group differences in memory task performance between people with and without SCD exist. The review included studies since 2014 comparing episodic memory performance between people with and without SCD; where people with SCD were recruited exclusively from community or medical settings. Studies providing data for people with mild cognitive impairment (MCI) were included in a separate meta-analysis comparing SCD and MCI. A systematic search was conducted (PsycINFO, Web of Science, MEDLINE, CINAHL, PubMed on 11th August 2023). Risk of bias was assessed using the Quality Assessment of Diagnostic Accuracy Studies tool. 1,815 records were identified, of which 45 met inclusion criteria and were included in a random-effects meta-analysis (SCD N = 5,948, Non-SCD N = 8,468). Twenty-one studies additionally provided data for an MCI group (SCD N = 1,034, MCI N = 2,119). Results indicated people with SCD performed significantly worse than people without SCD (Hedges' g = -0.19, 95% CI = -0.26, -0.11) and significantly better than MCI participants (Hedges' g = 1.20, 95% CI = 0.94, 1.46). For both meta-analyses there was significant between-study heterogeneity. There was a significant risk of publication bias for the meta-analysis comparing SCD to Non-SCD. These results suggest detailed memory assessment may be sensitive to reduced objective memory performance in SCD. However, it is unclear whether the small effect size has clinical significance. Higher quality and larger studies are needed to rule out the influence of moderating factors on memory performance.

Indexed as

CognitionDementiaNeuropsychological assessmentSubjective cognitive decline

Identifiers

PMID41455054

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.