Evidence map›Paper›PMID 41455034›Full record

Trial reportCancer causes & control : CCC2025

Supporting informed decisions about breast cancer screening in communities with known environmental contamination: a pre-post study.

Mia St Angelo, Megan E Romano, Lisa Gallagher, Christine M Gunn

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in Cancer causes & control : CCC, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06098118 (Adapting a Mammography Decision Aid to Support Women Living in a Community Contaminated by Per- and Polyfluoroalkyl Substances), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06098118 nacompletednot on this map

Adapting a Mammography Decision Aid to Support Women Living in a Community Contaminated by Per- and Polyfluoroalkyl Substances (PFAS)

TypeinterventionalSponsorTrustees of Dartmouth CollegeRan2024 to 2024Enrolled100ConditionsBreast Cancer ScreeningArmsMyMammogram decision aid
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mia St AngeloThe Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth College, 1 Medical Center Dr, WTRB Level 5, Lebanon, NH, 03766, USA.
Megan E RomanoDepartment of Epidemiology, Geisel School of Medicine at Dartmouth College, Lebanon, NH, USA.
Lisa GallagherDepartment of Epidemiology, Geisel School of Medicine at Dartmouth College, Lebanon, NH, USA.
Christine M GunnThe Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth College, 1 Medical Center Dr, WTRB Level 5, Lebanon, NH, 03766, USA. Christine.M.Gunn@dartmouth.edu.ORCID http://orcid.org/0000-0003-3340-2834

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Fred W Kolling IV · 1985 to 2026
$91.3M
NCI NIH HHS P30 CA023108
6 · The paper itself

Abstract

purposeThis study tested the impact of a breast cancer screening decision aid (DA) that was adapted to include environmental risk information.

methodsThis was a pre-post study in communities with known per- and poly-fluoroalkyl substances (PFAS) contamination. Participants were 100 women ages 39-49, with no history of breast cancer and no mammogram in the past year. Participants completed a baseline survey, used the DA, then completed a final survey. Baseline surveys measured demographics, PFAS exposure, and PFAS-related risk perceptions. Paired pre-post survey measures included breast cancer risk perceptions, screening knowledge, decisional conflict, and screening intentions.

resultsMean age of participants was 43 years; most non-Hispanic white (97%); 43% resided in micropolitan, small town, or rural areas. Potential PFAS exposure included private well use for 35%; 19% had tested their water for PFAS contamination; 54% used a home water filter. While most (62%) did not experience PFAS-related stress, 27% felt stress about family well-being, and 25% often/constantly worried about the health effects of PFAS in the prior month. Pre-DA, 29% felt likely that they would develop breast cancer in the next 10 years, versus 19% post-DA. Median knowledge scores increased from 8 to 10 out of 10 before and after DA use. Intentions to get a mammogram in the next year slightly decreased from 85 to 78%.

conclusionUse of a DA incorporating information about environmental risk information reduced perceptions of breast cancer risk and improved knowledge and decisional conflict about breast cancer screening among women living in PFAS-contaminated communities. CLINICAL

trial registrationNCT06098118.

Indexed as

Breast NeoplasmsDecision MakingDecision Support TechniquesEarly Detection of CancerEnvironmental ExposureAdultFemaleHealth Knowledge, Attitudes, PracticeHumansMammographyMiddle AgedBreast cancerCancer screeningEnvironmental riskRisk communication

Identifiers

PMID41455034
PMCPMC13635951

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.