Evidence map›Paper›PMID 41455003›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025

Effectiveness of a stepped-care model to address fear of cancer recurrence in patients with early-stage melanoma: results at 6- and 12-month follow-up.

Jake R Thompson, Lisa Gomes, Grace Kouvelis, Andrea L Smith, Serigne N Lo, Nadine A Kasparian, Robyn P M Saw, Mbathio Dieng, Linda Seaman, Linda K Martin and 5 more

Abstract read
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In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jake R ThompsonFaculty of Medicine and Health, University of Sydney, Camperdown, NSW, Australia. jake.thompson@sydney.edu.au.ORCID http://orcid.org/0000-0002-0823-3218
Lisa GomesFaculty of Medicine and Health, University of Sydney, Camperdown, NSW, Australia.ORCID http://orcid.org/0009-0005-4004-3608
Grace KouvelisFaculty of Medicine and Health, University of Sydney, Camperdown, NSW, Australia.ORCID http://orcid.org/0000-0002-4116-383X
Andrea L SmithThe Daffodil Centre, the University of Sydney, a joint venture with Cancer Council NSW, Sydney, NSW, Australia.ORCID http://orcid.org/0000-0002-9194-4888
Serigne N LoMelanoma Institute Australia, University of Sydney, 40 Rocklands Road, Wollstonecraft, Sydney, NSW, 2065, Australia.ORCID http://orcid.org/0000-0001-5092-5544
Nadine A KasparianHeart and Mind Wellbeing Center, Heart Institute and the Division of Behavioural Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.ORCID http://orcid.org/0000-0001-8075-6817
Robyn P M SawFaculty of Medicine and Health, University of Sydney, Camperdown, NSW, Australia.ORCID http://orcid.org/0000-0002-3354-806X
Mbathio DiengNHMRC Clinical Trials Centre, University of Sydney, Camperdown, NSW, Australia.ORCID http://orcid.org/0000-0001-6714-9633
Linda SeamanMelanoma Institute Australia, University of Sydney, 40 Rocklands Road, Wollstonecraft, Sydney, NSW, 2065, Australia.
Linda K MartinMelanoma Institute Australia, University of Sydney, 40 Rocklands Road, Wollstonecraft, Sydney, NSW, 2065, Australia.ORCID http://orcid.org/0000-0001-9519-7077
Pascale GuiteraFaculty of Medicine and Health, University of Sydney, Camperdown, NSW, Australia.ORCID http://orcid.org/0000-0001-9519-110X
Donna MilneMelanoma and Skin Cancer Service, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.ORCID http://orcid.org/0000-0002-9874-2023
Helen SchmidCentre for Cancer Research, Westmead Institute for Medical Research, Sydney, NSW, Australia.
Anne E CustMelanoma Institute Australia, University of Sydney, 40 Rocklands Road, Wollstonecraft, Sydney, NSW, 2065, Australia.ORCID http://orcid.org/0000-0002-5331-6370
Iris BartulaFaculty of Medicine and Health, University of Sydney, Camperdown, NSW, Australia.ORCID http://orcid.org/0000-0002-4084-4115

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the effectiveness of the Melanoma Care Program, an evidence-based, psychological intervention delivered through a stepped-care model, to address fear of cancer recurrence (FCR) in patients with early-stage melanoma at 6- and 12-month follow-up, when implemented into routine practice.

methodsIndividuals with stage 0-II melanoma participated in FCR severity screening using the Fear of Cancer Recurrence Inventory. Participants with an FCR severity score of ≤ 12 were offered usual care. Participants with an FCR severity score of ≥ 13 were offered a psychoeducational booklet and a stepped-care model offering participants up to 5 psychotherapeutic telehealth sessions with a clinical psychologist. Multivariable linear mixed modelling was used to analyse outcomes at 1 week, 6 months, and 12 months post-intervention, including FCR severity (primary outcome), symptoms of depression, anxiety, and stress, melanoma-related knowledge, and health-related quality of life.

resultsOne hundred and forty-three participants (111 women, mean age of 54.6 years) were screened; 115 (80%) participants had an FCR severity score ≥ 13, and of these, 112 (97%) participated in the intervention. Seventy-four participants (66%) completed 12-month follow-up. Adjusted multivariable linear mixed modelling demonstrated that the significant reduction in FCR severity found at 1 week post-intervention (mean change from baseline: -3.79; 95% CI: -4.72, -2.85; p < 0.001) was maintained at 6 months (mean change from baseline: -4.28; 95% CI: -5.30, -3.27; p < 0.001) and 12 months (mean change from baseline: -4.59; 95% CI: -5.62, -3.57; p < 0.001).

conclusionsThe Melanoma Care Program maintained effectiveness at 6- and 12-month follow-up when implemented into routine clinical practice for people with early-stage melanoma.

Indexed as

FearMelanomaNeoplasm Recurrence, LocalSkin NeoplasmsAdultAgedAnxietyDepressionFemaleFollow-Up StudiesHumansLinear ModelsMaleMiddle AgedNeoplasm StagingQuality of LifeFear of cancer recurrenceImplementationMelanomaPsychological interventionScreeningStepped-care

Identifiers

PMID41455003

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.