SynthesisPediatric surgery international2025
Comparative efficacy of Soave versus Swenson procedures for Hirschsprung disease: a systematic review and meta-analysis.
Synthesis in Pediatric surgery international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
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Abstract
objectiveTo compare the efficacy of Soave and Swenson procedures in the treatment of Hirschsprung disease (HSCR) through meta-analysis, and to provide evidence-based support for surgical choice.
methodsA systematic search of Chinese and English databases was performed to identify clinical studies comparing the two procedures. Extracted outcomes included perioperative parameters, postoperative complications, and long-term bowel function. Data were analyzed using Review Manager 5.4.1 and Stata 17.0.
resultsEleven retrospective cohort studies involving 972 children (506 Soave, 466 Swenson) were included. Compared with Soave, Swenson was associated with shorter operative time (MD: 26.39 min; 95% CI: 11.32-41.46; P < 0.001), reduced intraoperative blood loss (MD: 15.53 ml; 95% CI: 13.83-17.24; P < 0.001), and shorter postoperative hospital stay (MD: 1.50 days; 95% CI: 0.27-2.72; P = 0.02). No significant differences were found in early complications. Postoperative constipation was less frequent after Swenson (OR = 2.20; 95% CI: 1.04-4.64; P = 0.04), while no significant differences were observed for Hirschsprung-associated enterocolitis (HAEC), urinary retention, or other long-term outcomes.
conclusionThe Soave and Swenson procedures each have their own characteristics. Swenson improves surgical efficiency and reduces constipation, while Soave, with its clearer anatomical planes, may lower the risk of pelvic nerve injury and remains widely applied. Surgical choice should be individualized, and prospective multicentre studies are needed to optimize long-term outcomes in HSCR.
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