ReviewPalliative medicine2026
Palliative management of malignant gastric outlet obstruction: A practice review.
Review in Palliative medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMalignant gastric outlet obstruction is a frequent complication in advanced gastric, pancreatic and duodenal cancers, and can cause nausea, vomiting, pain, and malnutrition. No individual guideline comprehensively addresses the palliative management of malignant gastric-outlet-obstruction symptoms.
aimTo develop evidence-based recommendations for non-surgical palliative management of malignant gastric-outlet-obstruction, incorporating pharmacological, decompressive, endoscopic and nutritional strategies.
designPractice review using scoping methodology to evaluate the strength of evidence supporting guideline-recommended interventions. DATA SOURCES: We identified relevant national and international guidelines via web searches and the TRIP database; guideline reference lists were hand-searched for relevant primary studies; a supplementary structured MEDLINE search (2024) captured emerging research.
resultsA multidisciplinary team approach, with early evaluation of prognosis and patient preference, should guide intervention choice. Pharmacological therapies (opioids, antiemetics, antisecretory agents) are frequently used for symptom control, but evidence of their efficacy in malignant gastric-outlet-obstruction is limited. Duodenal stenting remains first-line for endoscopic palliation, while endoscopic gastroenterostomy has emerging evidence supporting its effectiveness and should be considered. Nasogastric or venting gastrostomy decompression is advised for acute obstruction when endoscopy is not feasible, but prolonged NG tube use should be avoided. Early nutritional assessment is recommended, although the optimal modality and duration of nutritional supplementation have yet to be determined.
conclusionsPatient-centred, multidisciplinary care is essential for malignant gastric-outlet-obstruction palliation. Further research is needed to establish optimal drug combinations. Duodenal stenting remains first-line, but guidelines should incorporate newer minimally-invasive interventions such as endoscopic gastroenterostomy. Standardised quality-of-life measures are required for developing integrated care pathways.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.