ArticleBMC musculoskeletal disorders2025
Intramedullary and extramedullary tibial alignment guides applied to each knee of the same patient resulted in no significant differences in radiological or clinical outcomes.
Article in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe superiority of intramedullary versus extramedullary alignment guides in total knee arthroplasty remains controversial, with previous studies reporting inconsistent results. Unlike studies comparing different patient groups, this study controlled for inter-patient variables by applying each method to the left and right knees of the same patients.
methodsWe retrospectively reviewed 344 patients (688 knees) who underwent bilateral TKA between March 2012 and December 2023. After excluding cases with the same guide used for both knees, revision procedures, PROSTALAC insertion, and loss to follow-up, 94 knees (47 patients) were analyzed. Each patient received IM guidance in one knee and EM guidance in the other, performed by a single experienced surgeon using a standardized technique. Radiological parameters (hip-knee-ankle axis, medial proximal tibial angle, joint line convergence angle, posterior tibial slope) and clinical measures (flexion contracture, further flexion, range of motion) were compared at a minimum of 12 months postoperatively.
resultsNo significant differences were found between IM and EM groups in postoperative radiological alignment (HKA axis, p = 0.308; MPTA, p = 0.523; JLCA, p = 0.984; posterior slope, p = 0.269) or clinical outcomes (flexion contracture, p = 0.339; further flexion, p = 0.724). Both methods achieved similar improvements from preoperative values.
conclusionsIM and EM guides provided comparable radiographic and clinical outcomes, allowing flexible selection based on patient anatomy and surgical conditions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.