Evidence map›Paper›PMID 41454314›Full record

ArticleBMC musculoskeletal disorders2025

Intramedullary and extramedullary tibial alignment guides applied to each knee of the same patient resulted in no significant differences in radiological or clinical outcomes.

Seung Joon Rhee, Kyeong Baek Kim, Won Chul Shin, Seung Hun Woo, Min Uk Do, Eun Sung Lee, Sang-Min Lee

Abstract readComparative Study
In one paragraph

Article in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

7 authors.

Seung Joon Rhee *Department of Orthopedic Surgery, Biomedical Research Institute, Pusan National University Hospital, Busan, Korea.
Kyeong Baek Kim *Pusan National University School of Medicine, Pusan National University, 20, Geumo-ro, Mulgeum-eup, Yangsan-si, Gyeongsangnam-do, Yangsan, Republic of Korea.
Won Chul ShinPusan National University School of Medicine, Pusan National University, 20, Geumo-ro, Mulgeum-eup, Yangsan-si, Gyeongsangnam-do, Yangsan, Republic of Korea.
Seung Hun WooPusan National University School of Medicine, Pusan National University, 20, Geumo-ro, Mulgeum-eup, Yangsan-si, Gyeongsangnam-do, Yangsan, Republic of Korea.
Min Uk DoPusan National University School of Medicine, Pusan National University, 20, Geumo-ro, Mulgeum-eup, Yangsan-si, Gyeongsangnam-do, Yangsan, Republic of Korea.
Eun Sung LeeDepartment of Orthopedic Surgery, Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, Republic of Korea.
Sang-Min LeePusan National University School of Medicine, Pusan National University, 20, Geumo-ro, Mulgeum-eup, Yangsan-si, Gyeongsangnam-do, Yangsan, Republic of Korea. dh62121@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe superiority of intramedullary versus extramedullary alignment guides in total knee arthroplasty remains controversial, with previous studies reporting inconsistent results. Unlike studies comparing different patient groups, this study controlled for inter-patient variables by applying each method to the left and right knees of the same patients.

methodsWe retrospectively reviewed 344 patients (688 knees) who underwent bilateral TKA between March 2012 and December 2023. After excluding cases with the same guide used for both knees, revision procedures, PROSTALAC insertion, and loss to follow-up, 94 knees (47 patients) were analyzed. Each patient received IM guidance in one knee and EM guidance in the other, performed by a single experienced surgeon using a standardized technique. Radiological parameters (hip-knee-ankle axis, medial proximal tibial angle, joint line convergence angle, posterior tibial slope) and clinical measures (flexion contracture, further flexion, range of motion) were compared at a minimum of 12 months postoperatively.

resultsNo significant differences were found between IM and EM groups in postoperative radiological alignment (HKA axis, p = 0.308; MPTA, p = 0.523; JLCA, p = 0.984; posterior slope, p = 0.269) or clinical outcomes (flexion contracture, p = 0.339; further flexion, p = 0.724). Both methods achieved similar improvements from preoperative values.

conclusionsIM and EM guides provided comparable radiographic and clinical outcomes, allowing flexible selection based on patient anatomy and surgical conditions.

Indexed as

Arthroplasty, Replacement, KneeKnee JointOsteoarthritis, KneeTibiaAgedAged, 80 and overFemaleHumansMaleMiddle AgedRadiographyRange of Motion, ArticularRetrospective StudiesTreatment OutcomeClinical outcomesExtramedullary alignmentIntramedullary alignmentOsteoarthritisRadiological outcomesTibial alignment guidesTotal knee arthroplasty

Identifiers

PMID41454314
PMCPMC12853634

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.