Evidence map›Paper›PMID 41454228›Full record

Trial reportBMC anesthesiology2025

Video laryngoscope versus disposcope endoscope for anticipated laryngeal tumor related difficult intubation in patients undergoing general anesthesia: a randomized controlled trial.

Hongyan Xiao, Yanan Xiao, Lili Feng, Yilei Shen, Liu Han, Yingjie Wang, Yirong Cai, Ji'e Jia, Peixia Wu, Yuan Han and 1 more

Abstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in BMC anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hongyan Xiao *Department of Anesthesiology, Eye & ENT Hospital of Fudan University, No.83 Fenyang Road, Xuhui District, Shanghai , 200031, China.
Yanan Xiao *Department of Anesthesiology, Eye & ENT Hospital of Fudan University, No.83 Fenyang Road, Xuhui District, Shanghai , 200031, China.
Lili FengDepartment of Anesthesiology, Eye & ENT Hospital of Fudan University, No.83 Fenyang Road, Xuhui District, Shanghai , 200031, China.
Yilei ShenDepartment of Anesthesiology, Eye & ENT Hospital of Fudan University, No.83 Fenyang Road, Xuhui District, Shanghai , 200031, China.
Liu HanDepartment of Anesthesiology, Xuzhou Maternity and Child Health Care Hospital Affiliated to Xuzhou Medical University, No. 46 Heping Road, Yunlong District, Xuzhou City, Jiangsu Province, 221000, China.
Yingjie WangDepartment of Anesthesiology, Eye & ENT Hospital of Fudan University, No.83 Fenyang Road, Xuhui District, Shanghai , 200031, China.
Yirong CaiDepartment of Anesthesiology, Eye & ENT Hospital of Fudan University, No.83 Fenyang Road, Xuhui District, Shanghai , 200031, China.
Ji'e JiaDepartment of Anesthesiology, Eye & ENT Hospital of Fudan University, No.83 Fenyang Road, Xuhui District, Shanghai , 200031, China.
Peixia WuVertigo and Balance Disorder Center, Eye & ENT Hospital of Fudan University, No.83 Fenyang Road, Xuhui District, Shanghai , 200031, China.
Yuan HanDepartment of Anesthesiology, Eye & ENT Hospital of Fudan University, No.83 Fenyang Road, Xuhui District, Shanghai , 200031, China.
Wenxian LiDepartment of Anesthesiology, Eye & ENT Hospital of Fudan University, No.83 Fenyang Road, Xuhui District, Shanghai , 200031, China. wenxian.li@fdeent.org.

Funding

Continuing Education Programs of Shanghai Medical College Fudan University FDYXYBJ-20222004Global Development Programs of Fudan University IDH6282016/049Perioperative Airway Refinement Management Programs of the Health Human Resources Development Center, National Health Commission RCLX2315001Shanghai Municipal Health Commission 202240315the National Natural Science Foundation of China 82271295the Natural Science Foundation of Shanghai 23ZR1409300
6 · The paper itself

Abstract

purposeLaryngeal tumors can cause significant anatomical distortion, making tracheal intubation challenging. Compared to video laryngoscope (VL), intubation using a Disposcope endoscope (DE) offers flexibility and allows for better navigation around obstructive lesions in the upper airway. This study aimed to compare the clinical performance of DE and VL for anticipated laryngeal tumor related difficult intubation in Ear, Nose, and Throat (ENT) patients undergoing general anesthesia.

methodsWe conducted a prospective, randomized, controlled trial. Eighty patients with anticipated difficult intubation due to laryngeal tumors undergoing elective surgery were included and randomly allocated to either the DE group (n = 40) or the VL group (n = 40). The primary outcome was the first-attempt success rate of tracheal intubation. Secondary outcomes included intubation time, hemodynamic response, and the incidence of complications related to intubation.

resultsA total of 80 subjects (61 male/19 female, 30 to 81 years old) were included in the final analysis. The first-attempt success rate of tracheal intubation was significantly higher in the DE group compared with the VL group (97.5% vs. 77.5%; mean difference [95% CI]: 20% [5.5 to 35.1]; P = 0.007). The intubation time was reduced in the DE group compared to the VL group (28.5 ± 6.7 s vs. 39.0 ± 10.0 s, mean difference [95% CI]: 10.5 s [6.7 to 14.3]; P < 0.001). Compared to DE, VL exhibited a higher heart rate one minute after intubation (71.1 ± 10.9 bpm vs. 78.3 ± 12.8 bpm; mean difference [95% CI]: 7.2 bpm [1.9 to 12.5]; P = 0.008). The incidence of postoperative airway complications was not significantly different between the two groups.

conclusionThe DE showed a higher first-attempt success rate and a shorter intubation time than the VL for anticipated laryngeal tumor related difficult intubation in ENT patients undergoing general anesthesia.

trial registrationChinese Clinical Trials Identifier ChiCTR2300068449.

Indexed as

Anesthesia, GeneralIntubation, IntratrachealLaryngeal NeoplasmsLaryngoscopesLaryngoscopyAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedProspective StudiesAnticipated difficult intubationDisposcope endoscopeGeneral anesthesiaLaryngeal tumorsVideo laryngoscope

Identifiers

PMID41454228
PMCPMC12866285

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.