Evidence map›Paper›PMID 41454149›Full record

ArticlePediatric research2026

Post-Traumatic Stress, depression and anxiety symptoms among childhood cancer survivors and their parents.

Maya Yardeni, Ilanit Hasson-Ohayon, Reut Pienik, Michal Mashiach-Eizenberg, Michal Ben Ami, Eve Stern, Hana Golan, Dalia Waldman, Amos Toren, Dalit Modan-Moses

Abstract read
In one paragraph

Article in Pediatric research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Maya YardeniDivision of Pediatric Hemato-Oncology, The Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Ramat-Gan, Israel. myardeni1@gmail.com.
Ilanit Hasson-OhayonDepartment of Psychology, Bar-Ilan University, Ramat-Gan, Israel.
Reut PienikDivision of Pediatric Endocrinology and Diabetes, The Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Ramat-Gan, Israel.
Michal Mashiach-EizenbergDepartment of Health Systems Management, Yezreel Valley Academic College, Yezreel Valley, Israel.
Michal Ben AmiDivision of Pediatric Endocrinology and Diabetes, The Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Ramat-Gan, Israel.
Eve SternDivision of Pediatric Endocrinology and Diabetes, The Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Ramat-Gan, Israel.
Hana GolanDivision of Pediatric Hemato-Oncology, The Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Ramat-Gan, Israel.
Dalia WaldmanDivision of Pediatric Hemato-Oncology, The Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Ramat-Gan, Israel.
Amos TorenDivision of Pediatric Hemato-Oncology, The Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Ramat-Gan, Israel.
Dalit Modan-MosesDivision of Pediatric Endocrinology and Diabetes, The Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Ramat-Gan, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMultiple studies demonstrated increased risk for psychological symptoms among childhood cancer survivors (CCS) and their parents. We aimed to assess the prevalence and severity of post-traumatic stress symptoms (PTSS), depression, and anxiety among CCS and their parents, examine associations between these measures, and identify potential risk factors.

methodsA cross-sectional study comprising 118 CCS aged 7-21 years and their parents, at least one year post-treatment. PTSS, depression and anxiety were assessed using validated questionnaires. Medical and sociodemographic data were collected from the medical charts.

resultsPTSD criteria were met by 8.7% of CCS and 18.3% of parents, about a third reporting post-traumatic stress symptoms. Moderate-to-severe depression occurred in 22% of CCS and 7.6% of parents, and anxiety in 12.7% of CCS and 22% of parents. There were robust positive correlations between depression, anxiety, and PTSS within both CCS and parental self-reports. Parents' proxy- reports correlated more strongly with their self-report than with CCS self-reports. Predictors of PTSS included time since diagnosis, parent's education, parent's sex, type of cancer, and depression and anxiety level.

conclusionsThe study highlights the importance of screening both children and parents, prioritizing child self-report, and providing tailored, ongoing psychosocial support for CCS and their families. IMPACT: Our study revealed high rates of psychological symptoms among CCS and their parents during the survivorship phase. The dual-informant design using pediatric self-report, parent self-report, and parent-proxy report enabled exploration of interconnections between psychological symptoms of CCS and their parents. Parents' perceptions of children's distress correlated more with their own emotional state than with children's self-reports, suggesting parental projection. Predictors of post-traumatic stress symptoms, including time since diagnosis, parental education and biological-sex, depression and anxiety. Our results emphasize the need for screening both children and parents, prioritizing child self-report, and providing tailored, ongoing psychosocial support for CCS and their families.

Indexed as

AnxietyCancer SurvivorsDepressionNeoplasmsParentsStress Disorders, Post-TraumaticAdolescentAdultChildCross-Sectional StudiesFemaleHumansMalePrevalenceRisk FactorsSelf Report

Identifiers

PMID41454149
PMCPMC13638459

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.