ArticleBMJ open2025
Are adverse socioeconomic conditions in childhood associated with intrinsic capacity in older age? A cross-sectional study from the Lausanne cohort Lc65.
Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Intergenerational educational mobility and intrinsic capacity in later life: a harmonised analysis of individuals from five countries.Journal of global health · 2026Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis study aimed to assess the associations between childhood adverse socioeconomic conditions and intrinsic capacity in older adults using an integrative approach to ageing.
designA cross-sectional study.
settingWe used data from the Lausanne Cohort 65+, a population-based longitudinal study that has been conducted in Lausanne, Switzerland, since 2004.
participantsLausanne citizens aged 67-71 years old. OUTCOMES: Intrinsic capacity was assessed in 2015 using validated self-reported measures and performance tests. Partial Least Squares Structural Equation Modelling was used in a formative approach to calculate the global score of intrinsic capacity and the scores of its domains. Adverse socioeconomic conditions in childhood were retrospectively assessed in 2014 using self-reported measures of financial strain, dietary restrictions and child labour.
resultsThe study sample included 1328 individuals. Multivariable regressions revealed that the global score of intrinsic capacity was lower in individuals who reported financial strain (B=-0.15, p=0.029) and dietary restrictions (B=-0.314, p=0.004) in childhood. They further showed an association between financial strain and lower locomotor and sensory capacities (B=-0.173, p=0.011 and B=-0.153, p=0.027, respectively), and between child labour and a lower score on cognition (B=-0.342, p<0.001).
conclusionsOur results emphasise the critical role of early life conditions in healthy ageing. They highlight the importance of financial support for families and access to nutrition.
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