ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2026
Association of left ventricular end-diastolic volume with core temperature and heart rate during very hot and dry heat stress in older adults.
Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
There is considerable heterogeneity in the thermal and cardiovascular responses to heat stress, even among older adults within a similar age range; hence, age alone may not predict heat-related risks. This variability may be in part explained by differences in cardiorespiratory fitness. We aimed to identify whether left ventricular end-diastolic volume (LVEDV), a characteristic of cardiorespiratory fitness, was associated with core temperatures and heart rate responses in older adults exposed to 3 h of very hot and dry heat stress. We hypothesized that individuals with smaller LVEDV would exhibit higher ending core temperature and heart rates following heat stress. Twenty-two older adults (73 ± 5 yr; 10 females) were exposed to 3 h of very hot and dry ambient heat stress (47°C, 15% relative humidity) with accompanying activities of daily living. We assessed thermal and cardiovascular responses at baseline and end-heating. End core temperature ranged from 37.4°C to 38.9°C, whereas end heart rate ranged from 53 to 113 beats/min. Baseline LVEDV was associated with end-heating core temperature (β = -0.018, SE = 0.004;
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.