Evidence map›Paper›PMID 41452564›Full record

ReviewMedical oncology (Northwood, London, England)2025

Engineered nanoparticles for endocrine tumor targeting, current progress and future outlook.

Maryam Aftab, Zubair Ahmed, Muneeb Ullah, Shahid Ullah Khan, Muhammad Naeem, Amjad Khan, Abdul Wahab

Abstract readReview
PubMed Publisher
In one paragraph

Review in Medical oncology (Northwood, London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maryam Aftab *Department of Biosciences, COMSATS University, Park Road 45520, Islamabad, Pakistan.
Zubair Ahmed *Department of Pharmacy, Kohat University of Science & Technology, Kohat, 26000, Khyber Pakhtunkhwa, Pakistan.
Muneeb UllahCollege of Pharmacy, Pusan National University, Busandaehak-ro sixty- three beon-gil two, Geoumjeong-gu, Busan, 46241, Republic of Korea.
Shahid Ullah KhanDepartment of Biomedical Sciences, College of Medicine, Dubai Medical University (COM, DMU), Dubai, 19099, United Arab Emirates.
Muhammad NaeemDepartment of Biological Sciences, National University of Medical Science, Islamabad, 46000, Pakistan.
Amjad KhanDepartment of Pharmacy, Kohat University of Science & Technology, Kohat, 26000, Khyber Pakhtunkhwa, Pakistan.
Abdul WahabDepartment of Pharmacy, Kohat University of Science & Technology, Kohat, 26000, Khyber Pakhtunkhwa, Pakistan. wahabscholar@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endocrine tumors are hormone-secreting tumors that pose significant challenges for diagnosis and treatment due to their complex biological processes, delayed detection, and poor response to existing therapies. Despite advancements in imaging, surgery, and medicine, tumor heterogeneity, substantial barriers, and systemic toxicity hinder therapeutic success. A novel approach utilizing nanotechnology presents theranostics capabilities for various applications, enhances bioavailability, and ensures precise drug delivery. Engineered nanoparticles (NPs), including lipid-based, polymeric, and inorganic nanocarriers, enable targeted therapy through active targeting (ligand-receptor interactions) or passive accumulation (increased permeability and retention). These nanotechnologies address drug resistance and rapid clearance, delivering treatments directly to tumors while minimizing adverse effects on healthy cells. NPs that mimic biological processes or respond to external stimuli can adapt to the evolving tumor microenvironment. This review focuses on NP-based therapy for endocrine cancer, discussing their mechanisms of action, targeted approaches, and diagnostic and therapeutic applications. The limitations of current therapies and the future prospects of NP-based therapies are explored.

Indexed as

Antineoplastic AgentsDrug Delivery SystemsEndocrine Gland NeoplasmsNanoparticlesAnimalsHumansAntineoplastic AgentsEndocrine tumorsEngineered nanoparticlesNanotechnologyTargeting tumors

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.